成功的小肠/肝脏移植。

Successful small-bowel/liver transplantation.

作者信息

Grant D, Wall W, Mimeault R, Zhong R, Ghent C, Garcia B, Stiller C, Duff J

机构信息

Department of Medicine, University of Western Ontario, London, Canada.

出版信息

Lancet. 1990 Jan 27;335(8683):181-4. doi: 10.1016/0140-6736(90)90275-a.

DOI:10.1016/0140-6736(90)90275-a

PMID:1967664

Abstract

A patient with the short-gut syndrome and antithrombin III deficiency underwent small bowel and liver grafting a year ago. Transient, mild graft-versus-host disease and intestinal rejection occurred within 2 months of grafting and were easily managed. Parenteral nutrition was discontinued 8 weeks after surgery. The patient has maintained normal nutritional indices while on an unrestricted oral diet. Small-bowel/liver grafting is feasible for patients with the short-gut syndrome and associated liver disorders. Further experience is needed to determine the specific risks, benefits, and general applicability of this procedure.

摘要

一名患有短肠综合征和抗凝血酶III缺乏症的患者于一年前接受了小肠和肝脏移植。移植后2个月内出现了短暂、轻度的移植物抗宿主病和肠道排斥反应，且易于处理。术后8周停止了肠外营养。患者在无限制的口服饮食情况下维持了正常的营养指标。对于患有短肠综合征及相关肝脏疾病的患者，小肠/肝脏移植是可行的。需要更多经验来确定该手术的具体风险、益处和普遍适用性。