Faculty of Veterinary Medicine, Department of Biochemistry, Uludag University, Gorukle Kampusu, 16059 Bursa, Turkey.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Nov;25(11):1313-7. doi: 10.1080/02652030802233472.
Honey samples, collected from the Southern Marmara region of Turkey, were analysed for erythromycin residues by liquid chromatography-mass spectrometry using electrospray ionization in the positive ion mode (LC-ESI-MS). Fifty samples, comprising chestnut, pine, linden and multi-flower honeys, were collected directly from hives and analyzed. The limit of detection and quantification were 6 and 20 ng g(-1), respectively, and recovery ranged from 85 to 89%. Four of the honey samples (8%) were found to be contaminated with erythromycin residues at concentrations ranging from 50 to 1776 ng g(-1). An erythromycin-fortified cake feeding assay was also performed in a defined hive to test the transfer of erythromycin residue to the honey matrix. In this test hive, the residue level in the honey, 3 months after dosing, was approximately 28 ng g(-1).
土耳其南部马尔马拉地区采集的蜂蜜样本，采用电喷雾正离子模式（LC-ESI-MS）的液相色谱-质谱法进行红霉素残留分析。共采集了 50 个样本，包括栗树、松树、菩提树和百花蜂蜜，直接从蜂巢中采集并进行分析。检测限和定量限分别为 6 和 20 ng g(-1)，回收率在 85%至 89%之间。发现其中 4 个蜂蜜样本（8%）受到污染，含有浓度范围在 50 至 1776 ng g(-1)的红霉素残留。还在一个确定的蜂巢中进行了红霉素强化蜂粮喂养试验，以测试红霉素残留转移到蜂蜜基质中的情况。在这个试验蜂巢中，给药 3 个月后，蜂蜜中的残留水平约为 28 ng g(-1)。
