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主动脉峡部创伤后病变

Post-traumatic lesions of the aortic isthmus.

作者信息

Giulini Stefano Maria, Bonardelli Stefano

机构信息

Department of Medical and Surgical Sciences, Università degli Studi-A.O. Spedali Civili, Brescia, Italy.

出版信息

Ann Ital Chir. 2009 Mar-Apr;80(2):89-100.

Abstract

Lesions of the isthmus are the most frequent among post-traumatic lesions of the thoracic aorta (LTA): almost always secondary to closed thoracic traumas (road accidents, falls, crushing, and explosions), they are rarely iatrogenic (operatory catheterisms) or caused by penetrating wounds. In the review of the literature concerned in the report, from the analysis of 89 bibliographic sources, we note that the etiopathogenesis and the pathophysiology of the LTA still entail a very high immediate mortality, but we also note that, in recent years, remarkable improvements have been made not only in prevention, first-aid, diagnostic definition and in the understanding of the development of the LTA, but above all in therapeutic results. The correct use of the conservative approach, particularly in the immediately post-traumatic phases, the increasingly wide-spread use of endovascular exclusion (T-EVAR), even if not without numerous technical difficulties, and the further improvement of open surgery, currently make it possible to guarantee the individual patient the treatment that can offer the best probabilities of success, at least immediately. Final development, and a more complete and rigorous assessment of the medium and long term results of TEVAR will allow the formulation of therapeutic strategies that are even better defined and increasingly simple to implement, on the basis of algorithms, such as the one proposed by the Authors.

摘要

峡部损伤是胸主动脉创伤性损伤(LTA)中最常见的:几乎总是继发于闭合性胸部创伤(道路交通事故、跌倒、挤压和爆炸),很少由医源性因素(手术导管插入术)或穿透性伤口引起。在该报告所涉及的文献综述中,通过对89篇文献来源的分析,我们注意到LTA的病因发病机制和病理生理学仍然导致非常高的即时死亡率,但我们也注意到,近年来,不仅在预防、急救、诊断定义以及对LTA发展的理解方面取得了显著进展,而且最重要的是在治疗结果方面。正确使用保守方法,特别是在创伤后即刻阶段,血管内隔绝术(T-EVAR)的使用越来越广泛,即使并非没有众多技术困难,以及开放手术的进一步改进,目前使得能够为个体患者保证提供至少在即刻具有最佳成功概率的治疗。TEVAR的最终发展以及对其中长期结果更完整和严格的评估,将允许根据算法制定甚至更明确且实施起来越来越简单的治疗策略,例如作者提出的算法。

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