Cirillo Michele, Li Pizzi Antonio, Gargiulo Giovanna, Frattolillo Fiorentina, Piantadosi Francesca, Mattera Concetta, Afeltra Luigi, Gennarelli Nicola
Area Funzionale di Chirurgia Generale ad indirizzo gastroenterico, Dipartimento di Oncologia, Endocrinologia e Chirurgia Generale, Università degli Studi di Napoli "Federico II".
Ann Ital Chir. 2009 Mar-Apr;80(2):131-4.
The increase in the average life led an increase of diseases, acute and chronic, not only cardiovascular and respiratory system, but also gastrointestinal. Likewise we see an increase in neoplastic lesions, sometimes diagnosed in advanced stage of disease, not susceptible to radical therapy. The purpose of this work is to evaluate the usefulness, reliability and security of colonoscopy in elderly patients, age 75 years or more. MATHERIALS END METHODS: We analysed 2407 colonoscopies, performed from January 2005 to December 2006 in Unit of Digestive Endoscopy of Gastrointestinal Surgery ("Federico II" University of Naples) and in Unit of Digestive Endoscopy of "Villa Maria Clinica" (Mirabella Eclano). Of these four hundred and sixty-nine patients (19.5%), 276 men and 139 women, were 75-years-old or more. Were considered indications to endoscopy completeness of the examination, findings, presence of any complications. In all patients were performed premedication with midazolam, 2,5-5 mg and floroglucina biidrata, 40-80 mg. The patients were constantly monitored with pulsiossimetro.
The colonoscopy was completed in 432/469 patients (92%). In 19 cases (4%) there was a neoplastic stenosis; other reasons for the failure of cecal intubation were the poor intestinal preparation (2.5%) and intolerance of the patient (1.5%). Were excluded patients in follow-up to previous surgery or polypectomy (33.5%). Other indications in the investigation were, in descending order, abdominal pain (32.8%), presence of anaemia (22.4%), rectal bleeding (19.2%), diarrhea or constipation (18.4%), presence of abdominal mass (72%). There were no complications observed, or local (perforation/bleeding), or general (cardio-respiratory or neurological). Most frequent findings were: diverticoular disease (34.4%), polyps (22.4%), cancer (12.8%), find colitis also aspecific (10.4%), hemorrhoids (8.8%). In 11.2% of patients colonoscopy was negative.
The endoscopic examination of the gastrointestinal tract is now practiced daily in almost all hospitals. The advanced age of patient, with the possible presence of diseases associated is not, in our opinion, a controindication. Although present in the literature trials that emphasize the possibility of a higher incidence of complications in elderly patients, our experience shows how this control is quite safe, if executed in appropriate and correct manner, thanks also to appropriate preparation/sedation and monitoring of the patient. Compared to other diagnostic methods, such as air contrast barium enema, the computed tomography and virtual colonoscopy, "traditional" colonoscopy has the undoubted and decisive advantage of being able to run biopsies, and complete removal of the lesion, as in the case of polypectomy. In our case we have seen a high number of elderly patients, well 469/2407, equivalent to 19.5%. A neoplastic lesion was found in 165 patients (35.2%) and of these over 80% has successfully received curative treatment (surgery or polipectomy).
平均寿命的延长导致疾病增加,包括急慢性疾病,不仅有心血管和呼吸系统疾病,还有胃肠道疾病。同样,我们也看到肿瘤性病变有所增加,有些在疾病晚期才被诊断出来,无法进行根治性治疗。这项工作的目的是评估结肠镜检查在75岁及以上老年患者中的有效性、可靠性和安全性。
我们分析了2005年1月至2006年12月在那不勒斯“费德里科二世”大学胃肠外科消化内镜科和“维拉玛丽亚诊所”(米拉贝拉埃克拉诺)消化内镜科进行的2407例结肠镜检查。其中469例患者(19.5%),年龄在75岁及以上,男性276例,女性139例。评估内镜检查的指征包括检查的完整性、检查结果、是否存在任何并发症。所有患者均使用咪达唑仑2.5 - 5毫克和二水合荧光素钠40 - 80毫克进行预处理。患者持续使用脉搏血氧仪进行监测。
469例患者中有432例(92%)完成了结肠镜检查。19例(4%)存在肿瘤性狭窄;盲肠插管失败的其他原因是肠道准备不佳(2.5%)和患者不耐受(1.5%)。曾接受过手术或息肉切除术的患者被排除在随访之外(33.5%)。检查中的其他指征依次为腹痛(32.8%)、贫血(22.4%)、直肠出血(19.2%)、腹泻或便秘(18.4%)、腹部肿块(7.2%)。未观察到任何并发症,无论是局部(穿孔/出血)还是全身(心肺或神经方面)。最常见的检查结果为:憩室病(34.4%)、息肉(22.4%)、癌症(12.8%)、非特异性结肠炎(10.4%)、痔疮(8.8%)。11.2%的患者结肠镜检查结果为阴性。
目前几乎所有医院都每天进行胃肠道内镜检查。我们认为,患者年龄较大且可能存在相关疾病并非禁忌证。尽管文献中有试验强调老年患者并发症发生率可能较高,但我们的经验表明,如果以适当正确的方式进行,这种检查是相当安全的,这也得益于对患者进行适当的准备/镇静和监测。与其他诊断方法,如气钡双重造影、计算机断层扫描和虚拟结肠镜检查相比,“传统”结肠镜检查具有能够进行活检以及如息肉切除时完全切除病变的毋庸置疑的决定性优势。在我们的病例中,我们看到了大量老年患者,达469/2407例,相当于19.5%。165例患者(35.2%)发现有肿瘤性病变,其中超过80%成功接受了根治性治疗(手术或息肉切除术)。