Sadick Neil, Sorhaindo Lian
Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.
Cutis. 2009 Jun;83(6):299-302.
A comparative split-face study of 20 participants with disseminated facial molluscum contagiosum (MC) and human immunodeficiency virus (HIV) infection was conducted to assess treatment with cryosurgery (left side of the face) versus trichloroacetic acid (TCA) 100% peels (right side of the face). A total of 2 treatments were administered at 4-week intervals. At week 8, treatment with TCA 100% proved to be superior to cryosurgery with an average reduction in lesion count of 90% versus 55%, respectively. Demonstrating a statistically significant rate of lesion clearance (P < or = .05), TCA 100% appears to be more effective than cryosurgery at treating disseminated facial MC lesions in the setting of HIV infection.
对20名患有播散性面部传染性软疣（MC）和人类免疫缺陷病毒（HIV）感染的参与者进行了一项对比性半脸研究，以评估冷冻手术（面部左侧）与100%三氯乙酸（TCA）脱皮术（面部右侧）的治疗效果。每隔4周进行一次，共进行2次治疗。在第8周时，100% TCA治疗被证明优于冷冻手术，病变数量平均减少率分别为90%和55%。100% TCA显示出具有统计学意义的病变清除率（P≤0.05），在治疗HIV感染情况下的播散性面部MC病变方面，100% TCA似乎比冷冻手术更有效。
