Loisance D, Dubois-Randé J L, Deleuze P, Okude J, Rosenval O, Geschwind H
Department of Cardiac Surgery, CHU Henri Mondor, France.
Lancet. 1990 Feb 24;335(8687):438-40. doi: 10.1016/0140-6736(90)90666-s.
The 'Hemopump', an axial flow pump, when inserted in the left ventricle brings about mechanical unloading of the ventricle, thus reducing the risk of cardiac arrest during coronary angioplasty. In this study eight very ill patients with unstable myocardial ischaemia and various contraindications for coronary artery surgery were selected for coronary angioplasty with insertion of the hemopump. Anatomical difficulties prevented insertion in three patients, but coronary angioplasty was carried out successfully with the pump in place in the other five. When the pump was working the cardiac index rose by an average of 23% (8-50%) and the pulmonary capillary wedge pressure fell by 17% (0-22%). Though electrocardiographic monitoring showed temporary rhythm instability during angioplasty in four of the five patients, there was no clinical deterioration. Four of the five patients are symptom-free on medical treatment and the other is well after surgical revascularisation.
“血液泵”是一种轴流泵,插入左心室时可实现心室的机械卸载,从而降低冠状动脉血管成形术期间心脏骤停的风险。在本研究中,选择了8例患有不稳定型心肌缺血且有各种冠状动脉手术禁忌证的重病患者进行冠状动脉血管成形术并插入血液泵。解剖学上的困难导致3例患者无法插入,但另外5例患者在血液泵就位的情况下成功进行了冠状动脉血管成形术。当泵工作时,心脏指数平均上升23%(8%-50%),肺毛细血管楔压下降17%(0%-22%)。尽管心电图监测显示5例患者中有4例在血管成形术期间出现短暂的节律不稳定,但并无临床恶化情况。5例患者中有4例经药物治疗后无症状,另1例在手术血运重建后情况良好。