Kato Manabu, Soga Norihito, Arima Kiminobu, Sugimura Yoshiki
Division of Nephro-Urologic Surgery and Andrology, Department of Reparative and Regenerative Medicine, Institute of Medical Life Science Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Int J Urol. 2009 Aug;16(8):699-701. doi: 10.1111/j.1442-2042.2009.02332.x.
A 33-year-old man was hospitalized for treatment of a left renal tumor. The radiological findings were consistent with those of a left renal cell carcinoma (RCC). Subsequently, a radical nephrectomy was carried out. Macroscopic examination showed that a well-demarcated tumor measuring 2.9 x 2.6 x 2.5 cm was present in the middle portion of the resected kidney. The cut surface of the tumor was grayish-white in color. Pathological examination of the resected specimen showed a mucinous tubular and spindle cell carcinoma of the kidney (MTSCC-K). MTSCC-K is a low-grade renal epithelial neoplasm that has recently been recognized as a specific entity in the World Health Organization 2004 classification of RCC. To our knowledge, 17 cases of MTSCC-K in Japan have been reported by Japanese investigators. To avoid administration of excessive adjuvant treatment to patients, pathologists and urologists should consider this newly recognized low-grade malignancy when diagnosing renal tumors.
一名33岁男性因左肾肿瘤住院治疗。影像学检查结果与左肾细胞癌(RCC)相符。随后进行了根治性肾切除术。大体检查显示,在切除的肾脏中部有一个边界清晰的肿瘤,大小为2.9×2.6×2.5 cm。肿瘤切面呈灰白色。切除标本的病理检查显示为肾黏液性管状和梭形细胞癌(MTSCC-K)。MTSCC-K是一种低级别肾上皮性肿瘤,最近在世界卫生组织2004年RCC分类中被确认为一种特定类型。据我们所知,日本研究人员已报告了17例日本的MTSCC-K病例。为避免对患者进行过度的辅助治疗,病理学家和泌尿科医生在诊断肾肿瘤时应考虑这种新认识的低级别恶性肿瘤。