自主神经阻滞剂对心率的影响：两个种族群体之间的比较。
The effect of autonomic blockers on heart rate: a comparison between two ethnic groups.
作者信息
Meyer E C, Sommers D K, Schoeman H S, Avenant J C
机构信息
Department of Pharmacology, University of Pretoria, South Africa.
出版信息
Br J Clin Pharmacol. 1990 Feb;29(2):254-6. doi: 10.1111/j.1365-2125.1990.tb03629.x.
The influence of autonomic blockers on the heart rate of ten Bushmen and eight White volunteers was studied. There were significant differences in heart rate response to atropine alone between the White's and Bushmen. However, after prior beta-adrenoceptor blockade, these differences were no longer significant. It is postulated that a varying pharmacogenetic sensitivity to autonomic blockers may result from inequality of vagal or sympathetic tone.
研究了自主神经阻滞剂对10名布须曼人和8名白人志愿者心率的影响。白人和布须曼人对单独使用阿托品的心率反应存在显著差异。然而，在预先进行β-肾上腺素能受体阻滞之后，这些差异不再显著。据推测，对自主神经阻滞剂的药物遗传敏感性差异可能源于迷走神经或交感神经张力的不平等。
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