传奇仍在继续……直至终结。

The SAGA continues...to the end.

作者信息

Smith Susan

机构信息

Department of Pathology, Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, 10016, USA.

出版信息

Mol Cell. 2009 Aug 14;35(3):256-8. doi: 10.1016/j.molcel.2009.07.011.

DOI:10.1016/j.molcel.2009.07.011

PMID:19683489

Abstract

In this issue of Molecular Cell, Atanassov et al. (2009) show that the GCN5-containing SAGA complex regulates telomere function via deubiquitination and stabilization of the telomere repeat binding factor TRF1.

摘要

在本期《分子细胞》杂志中，阿塔纳索夫等人（2009年）表明，含有GCN5的SAGA复合物通过去泛素化和稳定端粒重复序列结合因子TRF1来调节端粒功能。