Chung Ka-Fai, Tso Kwok-Chu, Chung Robert Ting-Yiu
Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China.
Compr Psychiatry. 2009 Sep-Oct;50(5):471-6. doi: 10.1016/j.comppsych.2008.10.001. Epub 2009 Jan 15.
The objective of the study was to determine the reliability and validity of a Chinese version of the Mood Disorder Questionnaire (MDQ) in the general population in Hong Kong.
One thousand five hundred eighteen adults aged at least 18 years were randomly drawn from the general population and interviewed using a lay-administered version of the MDQ. A subsample of 114 randomly selected participants received a telephone-based Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition. Six subjects were diagnosed to have bipolar disorder (bipolar I = 1, bipolar II = 4, and bipolar not otherwise specified = 1), 13 had substance/alcohol use disorder, and 95 had neither bipolar nor substance/alcohol use disorder. We determined the internal consistency, factor structure, and concurrent validity of the Chinese MDQ.
The Cronbach alpha coefficient of the Chinese MDQ was 0.78. Principal component analysis with varimax rotation indicated a "euphoria-irritability-racing thoughts" factor, an "energized-activity" factor, and a "risky behavior" factor, which explained 46.6% of the rotated variance. There were significant differences in MDQ scores between the bipolar and non-bipolar non-substance/alcohol use disorder groups. The performance of the Chinese MDQ for detecting bipolar disorder was limited by a low sensitivity. Using the original cutoff criterion, defined as clustering of 7 or more symptoms that caused moderate or severe problems, the sensitivity was 0%, whereas the overall specificity was 95.4%. Lowering the cutoff criterion to a symptom score of at least 7 that caused minor or more problems yielded the best sensitivity (0.50) and specificity (0.92).
The Chinese MDQ is a reliable and valid measure of bipolar disorder in the community.
本研究的目的是确定中文版心境障碍问卷（MDQ）在香港普通人群中的信度和效度。
从普通人群中随机抽取1518名年龄至少18岁的成年人，使用非专业人员管理的MDQ版本进行访谈。114名随机选择的参与者的子样本接受了基于电话的《精神障碍诊断与统计手册》第四版结构化临床访谈。6名受试者被诊断为双相情感障碍（双相I型 = 1例，双相II型 = 4例，未另行规定的双相情感障碍 = 1例），13名有物质/酒精使用障碍，95名既无双相情感障碍也无物质/酒精使用障碍。我们确定了中文版MDQ的内部一致性、因子结构和同时效度。
中文版MDQ的克朗巴赫α系数为0.78。采用方差最大化旋转的主成分分析表明存在一个“欣快-易激惹-思维奔逸”因子、一个“精力充沛-活动增多”因子和一个“危险行为”因子，它们解释了旋转方差的46.6%。双相情感障碍组与非双相情感障碍非物质/酒精使用障碍组的MDQ得分存在显著差异。中文版MDQ检测双相情感障碍的表现受到低敏感性的限制。使用最初的截断标准，即7个或更多导致中度或重度问题的症状聚类，敏感性为0%，而总体特异性为95.4%。将截断标准降低至至少7个导致轻度或更严重问题的症状得分时，敏感性最佳（0.50），特异性为（0.92）。
中文版MDQ是社区中双相情感障碍的可靠且有效的测量工具。
