Federal University of Ceará, Fortaleza, CE, Brazil.
Compr Psychiatry. 2012 Apr;53(3):308-12. doi: 10.1016/j.comppsych.2011.04.059. Epub 2011 May 31.
The Mood Disorder Questionnaire (MDQ) is a screening instrument for bipolar spectrum disorders already validated in many languages.
Patients from 2 psychiatric outpatient facilities were diagnosed with bipolar disorder (BD) type I and II and major depression according to the mood module of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID), Axis I Disorders--Clinician Version. In addition, a control group of healthy subjects was selected. The diagnostic interviews were used as the gold standard against which to investigate the performance of the MDQ. The MDQ was administered to 153 subjects, distributed among 4 groups. We analyzed the test reliability and discriminative capacity of the MDQ for the detection of patients with BD.
Based on the SCID, Axis I Disorders--Clinician Version, 52 subjects (33.3%) presented a bipolar spectrum disorder (type I, II, or not otherwise specified), 48 (32.4%) were diagnosed as having unipolar depressive disorder, whereas 54 (35.3%) were unaffected by any type of psychiatric disorder (had no psychiatric disorder according to SCID results). The sensitivity for bipolar disorder was 0.72 (bipolar I disorder, 0.81; bipolar II disorder, 0.58; and bipolar disorder not otherwise specified, 0.69), with specificity of 0.95. The Brazilian Portuguese MDQ demonstrated adequate internal consistency (Cronbach α = .87).
Recruiting patients attending tertiary services may inflate the performance of the MDQ.
The performance of the Brazilian Portuguese MDQ is comparable with other language validations. In a psychiatric outpatient sample, the Brazilian Portuguese MDQ proves to be a feasible and reliable screening instrument.
心境障碍问卷(MDQ)是一种用于筛查双相谱系障碍的工具,已在多种语言中得到验证。
来自 2 家精神病门诊的患者根据心境障碍模块的结构临床访谈进行诊断,用于诊断和统计手册,第四版(DSM-IV),轴 I 障碍-临床医师版本。此外,还选择了一组健康对照者。诊断访谈被用作调查 MDQ 性能的金标准。对 153 名受试者进行了 MDQ 测试,将他们分为 4 组。我们分析了 MDQ 对检测双相情感障碍患者的测试可靠性和区分能力。
根据 DSM-IV,轴 I 障碍-临床医师版本,52 名患者(33.3%)患有双相谱系障碍(I 型、II 型或未另作规定),48 名(32.4%)被诊断为单相抑郁障碍,而 54 名(35.3%)未受任何类型的精神障碍影响(根据 SCID 结果无精神障碍)。双相情感障碍的敏感性为 0.72(双相 I 障碍,0.81;双相 II 障碍,0.58;双相未另作规定,0.69),特异性为 0.95。巴西葡萄牙语 MDQ 具有良好的内部一致性(Cronbach α=0.87)。
招募参加三级服务的患者可能会夸大 MDQ 的表现。
巴西葡萄牙语 MDQ 的性能与其他语言验证相当。在精神病门诊样本中,巴西葡萄牙语 MDQ 被证明是一种可行且可靠的筛查工具。