果蝇的抗病毒RNA沉默和miRNA生物合成涉及ARS2。
Fly antiviral RNA silencing and miRNA biogenesis claim ARS2.
作者信息
Voinnet Olivier
机构信息
Institut de Biologie Moléculaire des Plantes, Université de Strasbourg, CNRS UPR 2357, 67084 Strasbourg Cedex, France.
出版信息
Cell Host Microbe. 2009 Aug 20;6(2):99-101. doi: 10.1016/j.chom.2009.08.002.
PMID:19683674
Abstract
In plants and invertebrates, small silencing RNAs function in antiviral defense and developmental patterning through pathways that were so far considered genetically distinct. In a recent issue of Cell, Sabin and colleagues report the identification of Drosophila Ars2, a protein required for both these small RNA-mediated functions.
摘要
在植物和无脊椎动物中，小干扰RNA通过迄今为止被认为在基因上不同的途径，在抗病毒防御和发育模式形成中发挥作用。在最近一期的《细胞》杂志上，萨宾及其同事报告了果蝇Ars2的鉴定，Ars2是这两种小RNA介导功能所必需的一种蛋白质。
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