Appignani Antonino, Prestipino Marco, Bertozzi Mirko, Nardi Niccolò, Falcone Fabrizio
Department of Pediatric Surgery, University of Perugia, Perugia, Italy.
J Urol. 2009 Oct;182(4):1521-7. doi: 10.1016/j.juro.2009.06.054. Epub 2009 Aug 15.
We analyzed a new urethra preserving approach, double-cross flap protection, during tubularized incised plate urethroplasty. We compared the results of 57 patients treated with this new procedure and 80 patients treated with 2 different techniques.
We studied 137 patients with hypospadias between October 2002 and March 2008. Patients were divided into 3 groups. Group 1 consisted of 40 patients (mean age 50 months) undergoing tubularized incised plate urethroplasty. Group 2 included 40 patients (mean age 48 months) undergoing tubularized incised plate urethroplasty with dorsal subcutaneous flap. Group 3 consisted of 57 patients (mean age 39 months) undergoing tubularized incised plate urethroplasty with 2 de-epithelialized preputial flaps twisted ventrally and sutured individually over the neourethra. All patients were operated on by the same surgeons. Statistical analysis of postoperative complications was performed by ANOVA and chi-square test.
In Group 1 fistula developed in 6 patients (15%) and was associated with stenosis of the neourethra in 4 (10%). In Group 2 fistula developed in 4 patients (10%). In Group 3 no fistula was observed, but mild stenosis of the neomeatus developed in 3 patients (5.3%), which was treated with dilation. Thus, the incidence of fistula in group 3 was significantly less (p = 0.015).
Double-cross flap protection is safe and significantly reduces the incidence of postoperative fistula.
我们分析了一种新的保留尿道方法——双交叉皮瓣保护法,用于管状切开板尿道成形术。我们比较了采用这种新方法治疗的57例患者与采用2种不同技术治疗的80例患者的治疗结果。
我们研究了2002年10月至2008年3月期间的137例尿道下裂患者。患者被分为3组。第1组包括40例(平均年龄50个月)接受管状切开板尿道成形术的患者。第2组包括40例(平均年龄48个月)接受带背侧皮下皮瓣的管状切开板尿道成形术的患者。第3组由57例(平均年龄39个月)接受管状切开板尿道成形术的患者组成,术中将2个去上皮化的包皮皮瓣向腹侧扭转并分别缝合于新尿道上。所有患者均由同一组外科医生进行手术。采用方差分析和卡方检验对术后并发症进行统计学分析。
第1组有6例(15%)发生瘘管,其中4例(10%)伴有新尿道狭窄。第2组有4例(10%)发生瘘管。第3组未观察到瘘管,但有3例(5.3%)出现尿道口轻度狭窄,经扩张治疗。因此,第3组的瘘管发生率显著更低(p = 0.015)。
双交叉皮瓣保护法安全且能显著降低术后瘘管的发生率。