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静脉全身麻醉与气管插管在儿童复发性呼吸道乳头状瘤病手术治疗中的比较

Comparison of intravenous general anaesthesia vs endotracheal intubation in the surgical management of juvenile onset recurrent respiratory papillomatosis.

作者信息

Lei Wenbin, Wen Weiping, Su Zhenzhong, Chai Liping, Feng Xia, Liu Kexuan, Jiang Aiyun, Zhu Xiaolin

机构信息

National Key Disciplines of Otorhinolaryngology, Otorhinolaryngology Hospital, Otorhinolaryngology Institute, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China.

出版信息

Acta Otolaryngol. 2010 Feb;130(2):281-5. doi: 10.3109/00016480903051643.

Abstract

CONCLUSIONS

Both intravenous general anaesthesia (IVGA) and general anaesthesia with endotracheal intubation (GA with ET) are applicable for the procedure of juvenile onset recurrent respiratory papillomatosis (JO-RRP). GA with ET was found to be better for JO-RRP patients with dyspnoea, as it provided better stabilization of the vital signs with fewer postoperative complications.

OBJECTIVES

To evaluate the safety and efficacy of two different anaesthetic techniques in the removal of JO-RRP.

METHODS

A total of 52 JO-RRP patients with mild dyspnoea were included in the study. Each case underwent two procedures, one by IVGA and the other by GA with ET. A total of 104 procedures were performed. The effectiveness and safety of the two anaesthetic techniques were pairwise compared.

RESULTS

There were no significant differences in anaesthetic recovery time, operative time or postoperative voice quality between the two anaesthetic groups. However, significant differences in heart rate, oxygen saturation and carbon dioxide saturation were observed. Some patients who underwent IVGA developed apnoea (28.8%) and laryngeal spasm (19.2%). These complications were not observed in the GA with ET group.

摘要

结论

静脉全身麻醉(IVGA)和气管插管全身麻醉(GA 伴 ET)均适用于青少年复发性呼吸道乳头状瘤病(JO-RRP)的手术。对于有呼吸困难的 JO-RRP 患者,GA 伴 ET 效果更佳,因为它能更好地稳定生命体征,且术后并发症更少。

目的

评估两种不同麻醉技术在 JO-RRP 手术中的安全性和有效性。

方法

本研究共纳入 52 例轻度呼吸困难的 JO-RRP 患者。每例患者均接受两种手术,一次采用 IVGA,另一次采用 GA 伴 ET。共进行了 104 例手术。对两种麻醉技术的有效性和安全性进行配对比较。

结果

两个麻醉组在麻醉恢复时间、手术时间或术后嗓音质量方面无显著差异。然而,在心率、血氧饱和度和二氧化碳饱和度方面观察到显著差异。一些接受 IVGA 的患者出现了呼吸暂停(28.8%)和喉痉挛(19.2%)。GA 伴 ET 组未观察到这些并发症。

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