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静脉注射钆剂显示梅尼埃病患者存在内淋巴积水。

Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Ménière's disease.

作者信息

Nakashima Tsutomu, Naganawa Shinji, Teranishi Masaaki, Tagaya Mitsuhiko, Nakata Seiichi, Sone Michihiko, Otake Hironao, Kato Ken, Iwata Tomoyuki, Nishio Naoki

机构信息

Department of Otorhinolaryngology, Nagoya University, Nagoya, Japan.

出版信息

Acta Otolaryngol. 2010 Mar;130(3):338-43. doi: 10.1080/00016480903143986.

DOI:10.1080/00016480903143986
PMID:19685358
Abstract

CONCLUSION

Visualization of endolymphatic hydrops became possible after intravenous gadolinium (Gd) injection in patients with Ménière's disease.

OBJECTIVE

To visualize endolymphatic hydrops after intravenous Gd injection.

METHODS

Gd (gadoteridol; 0.2 mmol/kg) was injected intravenously in three patients with unilateral Ménière's disease. We performed three-dimensional fluid attenuated inversion recovery (3D-FLAIR) and three-dimensional real inversion recovery (3D-real IR) magnetic resonance imaging (MRI) 4 h after the injection using a 3-Tesla MRI unit. We used a 32-channel array coil to obtain a high signal-to-noise ratio.

RESULTS

Endolymphatic hydrops was observed in the ears of patients with Ménière's disease. However, Gd concentration in the perilymph was lower compared with that obtained after intratympanic Gd injection.

摘要

结论

梅尼埃病患者静脉注射钆(Gd)后,内淋巴积水变得可以可视化。

目的

在静脉注射Gd后使内淋巴积水可视化。

方法

对3例单侧梅尼埃病患者静脉注射Gd(钆特醇;0.2 mmol/kg)。注射后4小时,使用3特斯拉磁共振成像(MRI)设备进行三维液体衰减反转恢复(3D-FLAIR)和三维真实反转恢复(3D-real IR)磁共振成像。我们使用32通道阵列线圈以获得高信噪比。

结果

在梅尼埃病患者的耳中观察到内淋巴积水。然而,与鼓室内注射Gd后相比,外淋巴中的Gd浓度较低。

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