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A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response.

作者信息

Kaiser Anton, Gaidzik Nikola, Westerlind Ulrika, Kowalczyk Danuta, Hobel Alexandra, Schmitt Edgar, Kunz Horst

机构信息

Johannes Gutenberg-Universität Main, Institut für Organische Chemie, Duesbergweg 10-14, 55128 Mainz, Germany.

出版信息

Angew Chem Int Ed Engl. 2009;48(41):7551-5. doi: 10.1002/anie.200902564.

DOI:10.1002/anie.200902564
PMID:19685547
Abstract
摘要

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A synthetic vaccine consisting of a tumor-associated sialyl-T(N)-MUC1 tandem-repeat glycopeptide and tetanus toxoid: induction of a strong and highly selective immune response.一种由肿瘤相关唾液酸化-T(N)-MUC1串联重复糖肽和破伤风类毒素组成的合成疫苗:诱导强烈且高度选择性的免疫反应。
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