己酮可可碱对肿瘤坏死因子和白细胞介素-6生成的不同作用。 - Suppr

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Differential effect of oxpentifylline on tumour necrosis factor and interleukin-6 production.

作者信息

Waage A, Sørensen M, Størdal B

出版信息

Lancet. 1990 Mar 3;335(8688):543. doi: 10.1016/0140-6736(90)90779-5.

DOI:10.1016/0140-6736(90)90779-5

PMID:1968555

Abstract

摘要

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Differential effect of oxpentifylline on tumour necrosis factor and interleukin-6 production.己酮可可碱对肿瘤坏死因子和白细胞介素-6生成的不同作用。

Lancet. 1990 Mar 3;335(8688):543. doi: 10.1016/0140-6736(90)90779-5.

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Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline.己酮可可碱对肿瘤坏死因子-α产生的细胞和分子调节

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Spurious tumor necrosis factor-alpha and interleukin-6 production by human monocytes from blood collected in endotoxin-contaminated vacutainer blood collection tubes.采自内毒素污染的真空采血管中的人单核细胞产生假性肿瘤坏死因子-α和白细胞介素-6

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ARDS, neutrophils, and pentoxifylline.急性呼吸窘迫综合征、中性粒细胞与己酮可可碱

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[The effect of dexamethasone dose and cell population composition on in vitro production of tumor necrosis factor and interleukin-6 by mononuclear cells in peripheral blood of man].[地塞米松剂量和细胞群体组成对人外周血单个核细胞体外产生肿瘤坏死因子和白细胞介素-6的影响]

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Modulation of the production of cytokines in titanium-stimulated human peripheral blood monocytes by pharmacological agents. The role of cAMP-mediated signaling mechanisms.药物制剂对钛刺激的人外周血单核细胞中细胞因子产生的调节作用。环磷酸腺苷（cAMP）介导的信号传导机制的作用。

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Production of interleukin-6 by human and murine mononuclear leukocytes stimulated with Plasmodium antigens is enhanced by pentoxifylline, and tumor necrosis factor secretion is reduced.己酮可可碱可增强人及鼠单核白细胞受疟原虫抗原刺激后白细胞介素-6的产生，并减少肿瘤坏死因子的分泌。

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The effect of pentoxifylline on the healing of intestinal anastomosis in rats with experimental obstructive jaundice.己酮可可碱对实验性梗阻性黄疸大鼠肠吻合口愈合的影响。

Surg Today. 2000;30(10):896-902. doi: 10.1007/s005950070041.

Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy.小鼠急性移植物抗宿主病中肠隐窝细胞凋亡由肿瘤坏死因子α介导而非FasL-Fas相互作用介导：己酮可可碱对黏膜萎缩发展的影响

Gut. 1999 Aug;45(2):229-35. doi: 10.1136/gut.45.2.229.

In vitro effects of oxpentifylline on inflammatory cytokine release in patients with inflammatory bowel disease.己酮可可碱对炎症性肠病患者炎性细胞因子释放的体外作用

Gut. 1997 Apr;40(4):475-80. doi: 10.1136/gut.40.4.475.

Roles of proinflammatory and anti-inflammatory cytokines in pathophysiology of bacterial meningitis and effect of adjunctive therapy.促炎和抗炎细胞因子在细菌性脑膜炎病理生理学中的作用及辅助治疗的效果

Infect Immun. 1996 Dec;64(12):4883-90. doi: 10.1128/iai.64.12.4883-4890.1996.

Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.环磷酸腺苷磷酸二酯酶抑制剂通过与“低亲和力”磷酸二酯酶4构象体相互作用来抑制人单核细胞产生肿瘤坏死因子α的证据。

Br J Pharmacol. 1996 Jun;118(3):649-58. doi: 10.1111/j.1476-5381.1996.tb15450.x.

Inhibitory effects of pentoxifylline on LPS-induced leukocyte adhesion and macromolecular extravasation in the microcirculation.己酮可可碱对脂多糖诱导的微循环中白细胞黏附和大分子渗出的抑制作用。

Inflamm Res. 1995 Jul;44(7):281-6. doi: 10.1007/BF02032569.

Infect Immun. 1993 Jun;61(6):2737-40. doi: 10.1128/iai.61.6.2737-2740.1993.

Production of TNF alpha by LPS-stimulated murine, rat and human blood and its pharmacological modulation.脂多糖刺激的小鼠、大鼠和人血液中肿瘤坏死因子α的产生及其药理学调节。

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