Rodriguez-Gil Diego J, Treloar Helen B, Miller Alexandra, Two Aimee, Iwema Carrie, Greer Charles A
Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520-8082, USA.
Ann N Y Acad Sci. 2009 Jul;1170:18-20. doi: 10.1111/j.1749-6632.2009.04366.x.
Odorant receptors are thought to be critical determinants of olfactory sensory neuron axon targeting and organization. Nonetheless, a systematic characterization of the onset of odorant receptor expression has not yet been done in the main olfactory epithelium. Here, we briefly review our current understanding regarding the onset of odorant receptor expression in the main olfactory epithelium and identify some of those questions which we believe must be of high priority for future study.
气味受体被认为是嗅觉感觉神经元轴突靶向和组织的关键决定因素。尽管如此,主嗅觉上皮中气味受体表达起始的系统特征尚未得到研究。在此,我们简要回顾一下目前对主嗅觉上皮中气味受体表达起始的理解,并指出一些我们认为未来研究必须优先解决的问题。