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精神运动兴奋剂药物对多动症儿童的影响真的自相矛盾吗?

Are the effects of psychomotor stimulant drugs on hyperactive children really paradoxical?

作者信息

Sahakian B J, Robbins T W

出版信息

Med Hypotheses. 1977 Jul-Aug;3(4):154-8. doi: 10.1016/0306-9877(77)90065-2.

DOI:10.1016/0306-9877(77)90065-2
PMID:19688
Abstract

The improved "attention" exhibited by hyperactive children treated with amphetamine-like compounds is postulated to be related to a normal action of these drugs in producing stereotyped behavior. Such activity can be conceptualised as an increased "focusing" of attention, which would be expected to aid performance in tasks involving sustained concentration of attention, but impair performance on tasks involving reversals in cognitive strategy. These behavioural actions of the drugs can be linked to the functioning of central dopaminergic mechanisms.

摘要

用类苯丙胺化合物治疗的多动症儿童所表现出的注意力改善,被假定与这些药物产生刻板行为的正常作用有关。这种活动可以被概念化为注意力的“聚焦”增加,这有望有助于涉及持续注意力集中的任务表现,但会损害涉及认知策略逆转的任务表现。这些药物的行为作用可以与中枢多巴胺能机制的功能联系起来。

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