Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Cancer Res Treat. 2008 Mar;40(1):1-5. doi: 10.4143/crt.2008.40.1.1. Epub 2008 Mar 31.
The goal of this study was to determine the clinical and epidemiological trends of cervical cancer in young Korean women. Social behavior including sexual habits has changed in Korean women, with sexual activity commencing at a younger age. These changes are likely to influence certain risk factors of cervical cancer, resulting in changing trends in the occurrence of the disease.
The incidence of cervical cancer in women less than 35 years-old between January 1990 and December 2006 was analyzed, and available medical records from January 1996 to December 2006 were reviewed. The clinical, pathological and epidemiologic characteristics and changing trends among these young patients were analyzed.
Over the last two decades, the incidence of young (< 35 years) cervical cancer patients increased, more patients had an aggressive form of the disease, and there was a higher rate of women with more advanced education. Human papillomavirus (HPV) infection was detected in 94.0% of the women (63/67) tested. HPV 16 (82.5%) and HPV 18 (12.7%) were the two most common viral infections detected throughout the study period.
The changing trends and risk factors identified suggest a need for more active education of young women about cervical cancer prevention strategies. In addition, young women are strongly recommended to undergo a regular screening test and HPV vaccination.
本研究旨在探讨韩国年轻女性宫颈癌的临床和流行病学趋势。韩国女性的社会行为包括性行为发生了变化，性活动开始得更早。这些变化可能会影响宫颈癌的某些风险因素，导致疾病发生趋势的变化。
分析了 1990 年 1 月至 2006 年 12 月期间年龄小于 35 岁的女性宫颈癌发病率，并回顾了 1996 年 1 月至 2006 年 12 月的现有病历。分析了这些年轻患者的临床、病理和流行病学特征及变化趋势。
在过去的二十年中，年轻（<35 岁）宫颈癌患者的发病率增加，更多患者患有侵袭性疾病，且具有较高教育程度的女性比例更高。接受检测的 67 名女性中有 94.0%（63/67）检测到人乳头瘤病毒（HPV）感染。HPV16（82.5%）和 HPV18（12.7%）是整个研究期间最常见的两种病毒感染。
所确定的变化趋势和风险因素表明，需要对年轻女性进行更多关于宫颈癌预防策略的积极教育。此外，强烈建议年轻女性定期进行筛查测试和 HPV 疫苗接种。
