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糖与氨基酸在肠道吸收中的相互抑制作用。

Mutual inhibition of sugars and amino acid intestinal absorption.

作者信息

Vinardell M P

机构信息

Dept. Ciéncies Fisiològiques Humanes i de la Nutrició, Facultat de Farmàcia, Universitat de Barcelona, Spain.

出版信息

Comp Biochem Physiol A Comp Physiol. 1990;95(1):17-21. doi: 10.1016/0300-9629(90)90003-b.

DOI:10.1016/0300-9629(90)90003-b
PMID:1968809
Abstract
  1. Intestinal absorption of sugars shows interaction with amino acids and vice versa. 2. The percentage of inhibition induced by a substrate depends on the type of substrate and the substance affected. 3. The mutual inhibition of monosaccharides and amino acids can be explained by five different hypotheses. 4. The most accepted hypotheses are the "allosteric interaction" and the "accelerated efflux". 5. From the results in the literature it is difficult to decide which of the two hypotheses is the more accurate.
摘要
  1. 糖类的肠道吸收表现出与氨基酸的相互作用,反之亦然。2. 一种底物诱导的抑制百分比取决于底物的类型和受影响的物质。3. 单糖和氨基酸的相互抑制可以用五种不同的假说来解释。4. 最被认可的假说是“变构相互作用”和“加速外排”。5. 根据文献中的结果,很难确定这两种假说中哪一种更准确。

相似文献

1
Mutual inhibition of sugars and amino acid intestinal absorption.糖与氨基酸在肠道吸收中的相互抑制作用。
Comp Biochem Physiol A Comp Physiol. 1990;95(1):17-21. doi: 10.1016/0300-9629(90)90003-b.
2
Transport of sugars or amino acids increases potassium efflux from isolated enterocytes.糖类或氨基酸的转运增加了分离的肠上皮细胞的钾外流。
FEBS Lett. 1983 Nov 14;163(2):203-6. doi: 10.1016/0014-5793(83)80819-9.
3
Intestinal absorption of sugars and amino acids.糖类和氨基酸的肠道吸收。
Am J Clin Nutr. 1960 Mar-Apr;8:137-46. doi: 10.1093/ajcn/8.2.137.
4
[Intestinal absorption in vivo and drugs. II. Action of some drugs on intestinal absorption of 2 amino acids and 2 sugars in rats].
Boll Soc Ital Biol Sper. 1967 Aug 31;43(16):953-6.
5
[Inhibition of intestinal absorption of sugars and amino acids by prenylamine (Segontin)].
Dtsch Med Wochenschr. 1972 Mar 10;97(10):394-6.
6
[Oses, holosides and polyols effect on intestinal absorption of some minerals and organic molecules (author's transl)].
Therapie. 1981 Nov-Dec;36(6):635-51.
7
Comparison of the effect of two different hypoglycemic agents, glibenclamide and HB 699, on the rat small intestinal absorption of sugars and amino acids.两种不同降糖药(格列本脲和HB 699)对大鼠小肠糖类和氨基酸吸收影响的比较。
Biochem Pharmacol. 1986 Sep 1;35(17):2929-35. doi: 10.1016/0006-2952(86)90488-0.
8
Enhancement of net sodium transport in isolated bullfrog intestine by sugars and amino acids.糖和氨基酸对离体牛蛙肠道净钠转运的增强作用。
Proc Soc Exp Biol Med. 1969 May;131(1):46-51. doi: 10.3181/00379727-131-33801.
9
Effects of sugars and amino acids on sodium and potassium influx in rabbit ileum.糖和氨基酸对兔回肠钠和钾内流的影响。
J Clin Invest. 1973 Jan;52(1):215-7. doi: 10.1172/JCI107169.
10
Stimulation of intestinal sodium absorption by sugars.
Am J Clin Nutr. 1970 Apr;23(4):437-40. doi: 10.1093/ajcn/23.4.437.

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