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在对患有严重肢体缺血的患者进行截肢前,务必联系血管介入专家。

Always contact a vascular interventional specialist before amputating a patient with critical limb ischemia.

机构信息

Department of Radiology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

出版信息

Cardiovasc Intervent Radiol. 2010 Jun;33(3):469-74. doi: 10.1007/s00270-009-9687-3. Epub 2009 Aug 18.

Abstract

Patients with severe critical limb ischemia (CLI) due to long tibial artery occlusions are often poor candidates for surgical revascularization and frequently end up with a lower limb amputation. Subintimal angioplasty (SA) offers a minimally invasive alternative for limb salvage in this severely compromised patient population. The objective of this study was to evaluate the results of SA in patients with CLI caused by long tibial occlusions who have no surgical options for revascularization and are facing amputation. We retrospectively reviewed all consecutive patients with CLI due to long tibial occlusions who were scheduled for amputation because they had no surgical options for revascularization and who were treated by SA. A total of 26 procedures in 25 patients (14 males; mean age, 70 +/- 15 [SD] years) were evaluated. Technical success rate was 88% (23/26). There were four complications, which were treated conservatively. Finally, in 10 of 26 limbs, no amputation was needed. A major amputation was needed in 10 limbs (7 below-knee amputations and 3 above-knee amputations). Half of the major amputations took place within 3 months after the procedure. Cumulative freedom of major amputation after 12 months was 59% (SE = 11%). In six limbs, amputation was limited to a minor amputation. Seven patients (28%) died during follow-up. In conclusion, SA of the tibial arteries seem to be a valuable treatment option to prevent major amputation in patients with CLI who are facing amputation due to lack of surgical options.

摘要

患有因长段胫骨动脉闭塞引起的严重肢体缺血性疾病(CLI)的患者通常不适合进行手术血运重建,并且最终往往需要进行下肢截肢。内膜下血管成形术(SA)为严重肢体缺血患者提供了一种微创的保肢替代治疗方法。本研究的目的是评估 SA 在 CLI 患者中的应用效果,这些患者因长段胫骨动脉闭塞而无法进行手术血运重建,并且面临截肢风险。我们回顾性分析了所有因长段胫骨动脉闭塞导致 CLI 且无手术血运重建选择、计划进行截肢的连续患者的病例资料,这些患者接受了 SA 治疗。共评估了 25 例患者(14 例男性;平均年龄 70 +/- 15[SD]岁)的 26 例次 SA 治疗。技术成功率为 88%(23/26)。有 4 例并发症,均经保守治疗处理。最终,26 条肢体中有 10 条无需截肢。10 条肢体需要进行大截肢(7 例为膝下截肢,3 例为膝上截肢)。大截肢中有一半发生在手术 3 个月内。12 个月时主要截肢的无截肢生存率为 59%(SE=11%)。在 6 条肢体中,截肢限制为小截肢。7 例患者(28%)在随访期间死亡。结论:对于因缺乏手术选择而面临截肢的 CLI 患者,SA 治疗可作为预防大截肢的有效治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca55/2868169/d09be420c798/270_2009_9687_Fig1_HTML.jpg

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