Norden Lillebil, Saxon Lars, Kåberg Martin, Käll Kerstin, Franck Johan, Lidman Christer
Department of Clinical Neuroscience, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Scand J Infect Dis. 2009;41(10):727-34. doi: 10.1080/00365540903159279.
This was a multicentre study with risk perception as the theoretical framework, investigating if risk behaviours change when injecting drug users (IDUs) are aware of their hepatitis C virus (HCV) status and had assessed the health consequences with HCV infection. Two hundred and thirteen participants aged 15-40 y were analysed. Sharing of needles and of other injecting equipment were common both among participants who reported HCV-positive status (74%, 95% confidence interval (CI) 65.3-80.1%) and among those who reported HCV status unknown (68%, 95% CI 56.0-78.4%). Participants associating very severe health consequences with HCV infection and those who did not know of any health consequences with HCV infection shared needles at almost the same rate (78%, 95% CI 62.5-87.7 vs 69%, 95% CI 8.0-78.9, respectively). Sharing of other injecting equipment was most common among participants with verified HCV-positive status (adjusted risk ratio 5.64, 95% CI 2.64-12.07). Knowledge of HCV status and assessment of health consequences with HCV infection were not enough to change injecting risk behaviours. Sharing of other injecting equipment was a more important risk factor than sharing needles for participants with verified HCV-positive status. It is suggested that professionals engage IDUs in risk analysis and open a dialogue about assessment in order to identify, quantify and characterize risks.
这是一项以风险认知为理论框架的多中心研究,旨在调查注射吸毒者(IDU)知晓自身丙型肝炎病毒(HCV)感染状况并评估HCV感染对健康的影响后,其风险行为是否会发生改变。对213名年龄在15至40岁的参与者进行了分析。在报告HCV检测呈阳性的参与者中(74%,95%置信区间(CI)65.3 - 80.1%)以及报告HCV感染状况未知的参与者中(68%,95% CI 56.0 - 78.4%),共用针头和其他注射器具的情况都很常见。将HCV感染与极其严重的健康后果联系起来的参与者以及那些不知道HCV感染会造成任何健康后果的参与者共用针头的比例几乎相同(分别为78%,95% CI 62.5 - 87.7和69%,95% CI 8.0 - 78.9)。在经证实HCV检测呈阳性的参与者中,共用其他注射器具的情况最为常见(调整风险比5.64,95% CI 2.64 - 12.07)。知晓HCV感染状况以及评估HCV感染对健康的影响不足以改变注射风险行为。对于经证实HCV检测呈阳性的参与者而言,共用其他注射器具比共用针头是更重要的风险因素。建议专业人员让注射吸毒者参与风险分析并开启关于评估的对话,以便识别、量化和描述风险。