Cologna Camila T, Marcussi Silvana, Giglio José R, Soares Andreimar M, Arantes Eliane C
Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-USP, Ribeirão Preto-SP, Brazil.
Protein Pept Lett. 2009;16(8):920-32. doi: 10.2174/092986609788923329.
Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), its long-chain Na(+)-channel toxins (NaTx), which include alpha- and beta-neurotoxins, short-chain K(+)-channel toxins (KTx), hyaluronidase, proteases and other peptides hitherto identified.
巴西金幽灵蝎被认为是南美洲最危险的蝎子,也是造成大多数致命病例的元凶。本综述将聚焦于巴西金幽灵蝎毒液(Tsv)、其长链钠通道毒素(NaTx),其中包括α-和β-神经毒素、短链钾通道毒素(KTx)、透明质酸酶、蛋白酶以及迄今已鉴定出的其他肽类。