Stierman Sarah C, Tierney Emily P, Shwayder Tor A
Department of Dermatology, Wayne State University, Dearborn, Michigan, USA.
Pediatr Dermatol. 2009 Jul-Aug;26(4):414-24. doi: 10.1111/j.1525-1470.2009.00938.x. Epub 2009 Jul 20.
Halo formation in association with congenital nevi is uncommon and is postulated to have an immunologic etiology. In this report, we present nine cases of patients with congenital nevi and vitiligo who uniquely developed both halo formation around the nevi in addition to vitiligo formation in distinctly separate locations. While the precise etiology of halo formation and vitiligo remains uncertain, several theories suggest that both phenomena result from an immunologic response to pigment cells, whether in the "normal" skin of vitiligo or in the excessively pigmented congenital nevus.
与先天性痣相关的晕轮形成并不常见，据推测其病因与免疫有关。在本报告中，我们呈现了9例患有先天性痣和白癜风的患者，他们除了在不同部位出现白癜风外，痣周围还独特地出现了晕轮形成。虽然晕轮形成和白癜风的确切病因仍不确定，但有几种理论认为，这两种现象都是对色素细胞的免疫反应所致，无论是白癜风“正常”皮肤中的色素细胞，还是色素过度沉着的先天性痣中的色素细胞。
