Naess Halvor, Brogger Jan C, Idicula Titto, Waje-Andreassen Ulrike, Moen Gunnar, Thomassen Lars
Department of Neurology, Haukeland University Hospital, 5021 Bergen, Norway.
BMC Neurol. 2009 Aug 18;9:44. doi: 10.1186/1471-2377-9-44.
No large study has compared the yield of diffusion-weighted imaging (DWI) with clinical examination in order to differentiate lacunar stroke from other stroke subtypes. This differentiation is important for guiding further investigations and treatment.
Consecutive patients admitted with cerebral infarction were classified according to the Oxfordshire Community Stroke Project scale. Based on DWI and CT stroke was classified as lacunar (LI) and non-lacunar (NLI). Acute ischemic lesion <1.5 cm and located in subcortex or in brainstem were classified as LI. All other infarctions were classified as NLI.
DWI was performed in 419 (69%) patients. Among patients with lacunar syndrome (LACS) 45 (40.5%) had NLI on DWI. All patients with total anterior syndrome (TACS) and 144 (88.3%) with partial anterior syndrome (PACS) had NLI on DWI.
DWI is important among patients presenting with clinical symptoms suggestive of lacunar syndrome to differentiate between LI and NLI. On the other hand, there is good correspondence between TACS or PACS and NLI on DWI.
尚无大型研究对弥散加权成像(DWI)与临床检查在区分腔隙性卒中与其他卒中亚型方面的诊断价值进行比较。这种区分对于指导进一步的检查和治疗很重要。
根据牛津郡社区卒中项目量表对连续收治的脑梗死患者进行分类。基于DWI和CT,将卒中分为腔隙性(LI)和非腔隙性(NLI)。急性缺血性病灶<1.5 cm且位于皮质下或脑干的被分类为LI。所有其他梗死均分类为NLI。
419例(69%)患者接受了DWI检查。在腔隙综合征(LACS)患者中,45例(40.5%)DWI显示为NLI。所有完全前循环综合征(TACS)患者以及144例(88.3%)部分前循环综合征(PACS)患者DWI显示为NLI。
对于表现出腔隙综合征临床症状的患者,DWI在区分LI和NLI方面很重要。另一方面,TACS或PACS与DWI上的NLI之间存在良好的对应关系。