Malinzak Elizabeth B, Gan Tong J
Department of Anesthesiology, Duke University Medical Center, Duke University School of Medicine, Durham, NC 27710, USA.
Anesth Analg. 2009 Sep;109(3):976-80. doi: 10.1213/ane.0b013e3181adc208.
Approximately 25% of initial arteriovenous fistula (AVF) placements will fail as a result of thrombosis or failure to develop adequate vessel size and blood flow. Fistula maturation is impacted by patient characteristics and surgical technique, but both increased vein diameter and high fistula blood flow rates are the most important predictors of successful AVFs. Anesthetic techniques used in vascular access surgery (monitored anesthesia care, regional blocks, and general anesthesia) may affect these characteristics and fistula failure.
We performed a literature search using key words in the PubMed/MEDLINE database. Seven articles that related to the effects of anesthesia on AVF construction, including sympathetic block, vein dilation, blood flow, adverse outcomes, or patency rates, comprised the sources for this review.
Significant vasodilation after regional block administration is seen in both the cephalic and basilic veins. These vasodilatory properties may assist with AVF site selection. In the intraoperative and postoperative periods, use of a regional block, compared with other anesthetic techniques, resulted in significantly increased fistula blood flow. The greater sympathetic block contributed to vessel dilation and reduced vasospasm. Use of regional techniques in AVF construction yielded shorter maturation times, lower failure rates, and higher patency rates.
Use of regional blocks may improve the success of vascular access procedures by producing significant vasodilatation, greater fistula blood flow, sympathectomy-like effects, and decreased maturation time. However, a large-scale, prospective, clinical trial comparing the different anesthetic techniques is still needed to verify these findings.
由于血栓形成或未能形成足够的血管尺寸和血流量,约25%的初始动静脉内瘘(AVF)植入会失败。内瘘成熟受患者特征和手术技术影响,但静脉直径增加和高内瘘血流量都是成功的AVF的最重要预测因素。血管通路手术中使用的麻醉技术(监护麻醉、区域阻滞和全身麻醉)可能会影响这些特征和内瘘失败情况。
我们在PubMed/MEDLINE数据库中使用关键词进行了文献检索。七篇与麻醉对AVF构建的影响相关的文章,包括交感神经阻滞、静脉扩张、血流量、不良结局或通畅率,构成了本综述的资料来源。
区域阻滞给药后,头静脉和贵要静脉均出现明显的血管扩张。这些血管扩张特性可能有助于AVF部位的选择。在术中和术后,与其他麻醉技术相比,使用区域阻滞导致内瘘血流量显著增加。更强的交感神经阻滞有助于血管扩张并减少血管痉挛。在AVF构建中使用区域技术可缩短成熟时间、降低失败率并提高通畅率。
使用区域阻滞可能通过产生显著的血管扩张、更大的内瘘血流量、类似交感神经切除术的效果以及缩短成熟时间来提高血管通路手术的成功率。然而,仍需要一项比较不同麻醉技术的大规模、前瞻性临床试验来验证这些发现。