Rabkin J G, Harrison W M
New York State Psychiatric Institute, NY 10032.
Am J Psychiatry. 1990 Apr;147(4):495-7. doi: 10.1176/ajp.147.4.495.
Eleven men with major depression and human immunodeficiency virus (HIV) infection underwent an open trial of imipramine. Eight of nine (89%) who completed 12 weeks responded. The mean decline in T4 cells from baseline was 100 at week 12 and 16 at week 26. No major exacerbations of HIV infection occurred.
11名患有重度抑郁症且感染了人类免疫缺陷病毒（HIV）的男性接受了丙咪嗪的开放性试验。9名完成12周治疗的患者中有8名（89%）有反应。在第12周时，T4细胞较基线水平平均下降100，在第26周时下降16。未发生HIV感染的重大恶化情况。
