Clark D B, Taylor C B, Roth W T, Hayward C, Ehlers A, Margraf J, Agras W S
Department of Psychiatry, Stanford University Medical Center, Calif.
Am J Psychiatry. 1990 Apr;147(4):507-9. doi: 10.1176/ajp.147.4.507.
In a double-blind, placebo-controlled trial comparing alprazolam and imipramine for panic disorder, serum analysis revealed that a substantial proportion of the patients took explicitly prohibited anxiolytic medication. Excluding these patients changed the results.