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用于探测神经回路和治疗疾病的无创技术:迷走神经刺激(VNS)、经颅磁刺激(TMS)和经颅直流电刺激(tDCS)。

Noninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).

机构信息

Departments of Psychiatry, Radiology and Neuroscience, Institute of Psychiatry, MUSC Center for Advanced Imaging Research, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

Neuropsychopharmacology. 2010 Jan;35(1):301-16. doi: 10.1038/npp.2009.87.

DOI:10.1038/npp.2009.87
PMID:19693003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3055429/
Abstract

Although the preceding chapters discuss much of the new knowledge of neurocircuitry of neuropsychiatric diseases, and an invasive approach to treatment, this chapter describes and reviews the noninvasive methods of testing circuit-based theories and treating neuropsychiatric diseases that do not involve implanting electrodes into the brain or on its surface. These techniques are transcranial magnetic stimulation, vagus nerve stimulation, and transcranial direct current stimulation. Two of these approaches have FDA approval as therapies.

摘要

虽然前面的章节讨论了许多神经精神疾病的神经回路的新知识和侵入性治疗方法,但本章描述和回顾了非侵入性的测试基于回路的理论和治疗神经精神疾病的方法,这些方法不涉及将电极植入大脑或其表面。这些技术包括经颅磁刺激、迷走神经刺激和经颅直流电刺激。其中两种方法已获得 FDA 的批准作为治疗方法。

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2
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Brain Stimul. 2009 Apr;2(2):58-80. doi: 10.1016/j.brs.2008.11.002. Epub 2009 Feb 28.
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Corticomotor responses to triple-pulse transcranial magnetic stimulation: Effects of interstimulus interval and stimulus intensity.三脉冲经颅磁刺激的皮质运动反应:刺激间隔和刺激强度的影响。
Brain Stimul. 2009 Jan;2(1):36-40. doi: 10.1016/j.brs.2008.06.255. Epub 2008 Oct 7.
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Controversy: Repetitive transcranial magnetic stimulation or transcranial direct current stimulation shows efficacy in treating psychiatric diseases (depression, mania, schizophrenia, obsessive-complusive disorder, panic, posttraumatic stress disorder).争议:重复经颅磁刺激或经颅直流电刺激在治疗精神疾病(抑郁症、躁狂症、精神分裂症、强迫症、惊恐症、创伤后应激障碍)方面显示出疗效。
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