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嗅觉障碍:对泰国第一家嗅觉与味觉诊所的132名患者的研究。

Smell disorders: a study of 132 patients from the first Smell and Taste Clinic of Thailand.

作者信息

Kaolawanich Apichai, Assanasen Paraya, Tunsuriyawong Prayuth, Bunnag Chaweewan, Tantilipikorn Pongsakorn

机构信息

Department ofOtorhinolaryngology, Faculty ofMedicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2009 Aug;92(8):1057-62.

Abstract

OBJECTIVE

To investigate types and possible causes of smell disorders in patients who attended the Smell and Taste Clinic, Siriraj Hospital.

MATERIAL AND METHOD

Medical records of patients with smell disorders who attended the Smell and Taste Clinic, Siriraj Hospital between July 2002 and August 2005 were reviewed for gender age, duration of complaint, severity (hyposmia or anosmia), and previous medical illnesses (e.g., upper respiratory tract infection (URI), head injury, sinonasal problems, etc). All patients had complete physical examination, nasal endoscopy, and phenyl ethyl alcohol (PEA) olfactory threshold test.

RESULTS

One hundred and eighty eight patients' medical records were reviewed. Smell disorders were confirmed in 132 cases (male=58, female=74). Nearly an equal number of anosmia and hyposmia cases were found (50.8% and 49.2% respectively). Possible causes of smell disorders were categorized as follows: sinonasal disease (SND) (66.7%), head injury (12.1%), idiopathic cause (10.6%), URI (6.8%), congenital cause (3%), and others (0.8%). SND was the most common cause of smell disorders despite different age groups and duration of smell disorders. PEA test scores were higher in head injury and idiopathic groups compared with those in SND and post URI groups.

CONCLUSION

The present data showed that SND was the major cause of smell disorders in every age group and in each duration group followed by head injury, idiopathic cause, and URI respectively. Therefore, nasal endoscopy is highly recommended for every patient with smell disorders.

摘要

目的

调查诗里拉吉医院嗅觉与味觉门诊患者嗅觉障碍的类型及可能病因。

材料与方法

回顾2002年7月至2005年8月期间在诗里拉吉医院嗅觉与味觉门诊就诊的嗅觉障碍患者的病历,了解其性别、年龄、主诉持续时间、严重程度(嗅觉减退或嗅觉丧失)以及既往病史(如,上呼吸道感染(URI)、头部损伤、鼻窦问题等)。所有患者均接受了全面的体格检查、鼻内镜检查以及苯乙醇(PEA)嗅觉阈值测试。

结果

共回顾了188例患者的病历。确诊嗅觉障碍患者132例(男性58例,女性74例)。嗅觉丧失和嗅觉减退病例数相近(分别为50.8%和49.2%)。嗅觉障碍的可能病因分类如下:鼻窦疾病(SND)(66.7%)、头部损伤(12.1%)、特发性病因(10.6%)、URI(6.8%)、先天性病因(3%)以及其他(0.8%)。尽管患者年龄组和嗅觉障碍持续时间不同,SND仍是嗅觉障碍最常见的病因。与SND组和URI后组相比,头部损伤组和特发性病因组的PEA测试得分更高。

结论

目前的数据表明,SND是各年龄组和各病程组嗅觉障碍的主要病因,其次分别是头部损伤、特发性病因和URI。因此,强烈建议每一位嗅觉障碍患者都进行鼻内镜检查。

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