Fracasso Tony, Vennemann Mechtild, Pfeiffer Heidi, Bajanowski Thomas
Institute of Legal Medicine, University of Münster, Germany.
Am J Forensic Med Pathol. 2009 Sep;30(3):231-4. doi: 10.1097/PAF.0b013e318187e0f2.
Despite its decreasing incidence, sudden infant death syndrome (SIDS) still remains an important cause of death in infancy. Since Felix Platter described the case of a child suffocated because of a massive goiter (Platter E. Suffocatio a struma interna abscondita, circa iugulum. Observationum in hominis affectibus plerisque corpori et animo, functionum lesione, dolore, aliave molestia et vitio incommodantibus. Libris tres, Part IX. Basel: König and Brandmylieri; 1614), many authors have attempted to verify the existence of a correlation between the dimensions of organs of infants and SIDS. The lack of recent published norms and the difficulty in finding a suitable control group by which to compare the cases of SIDS shows the importance of this study.This article presents the organ weights of 209 male and 132 female babies whose cause of death was SIDS. The data have been collected from 2 different studies: the Westphalian Cot Death Study from 1990 to 1994 and the German National Study on SIDS from 1998 to 2001. The organ weights increased from month to month during the first year of life showing a tendency towards higher weights in males compared with females (these are, however, not statistically significant). No significant differences compared with the recently published data of Thompson and Cohle, J Forensic Sci. 2004;49:575-585 were found.The heart weights were compared with a control group of 47 babies (21 females, 26 males) died because of both natural and unnatural causes. The weight of the organs that presented macro-microscopical pathologic changes was excluded.The weights of the heart were also compared with those published by Schulz and Giordano, Arch Pathol. 1962;74:464-471 and Kelmanson, Eur J Pediatr. 1996;155:440-444. This comparison showed minor differences which are discussed in the article. We suggest that organ weights obtained in SIDS cases can be used as norms in the first year of life.
尽管婴儿猝死综合征（SIDS）的发病率在下降，但它仍是婴儿期重要的死亡原因。自费利克斯·普拉特描述了一例因巨大甲状腺肿导致儿童窒息的病例（普拉特E. 因颈部隐匿性内甲状腺肿导致的窒息。关于人体多种情感、身体和精神功能损伤、疼痛、其他不适和缺陷的观察。三卷本，第九部分。巴塞尔：柯尼希和布兰德米利耶里出版社；1614年）以来，许多作者试图验证婴儿器官大小与SIDS之间是否存在关联。近期缺乏已发表的标准，且难以找到合适的对照组来与SIDS病例进行比较，这表明了本研究的重要性。本文呈现了209名男婴和132名女婴的器官重量，这些婴儿的死因是SIDS。数据收集自两项不同的研究：1990年至1994年的威斯特法伦婴儿猝死研究以及1998年至2001年的德国全国婴儿猝死研究。在生命的第一年中，器官重量逐月增加，男性的器官重量有高于女性的趋势（然而，这些差异无统计学意义）。与汤普森和科尔近期发表的数据（《法医学杂志》。2004年；49:575 - 585）相比，未发现显著差异。将心脏重量与一组47名因自然和非自然原因死亡的婴儿（21名女性，26名男性）进行比较。排除了出现宏观 - 微观病理变化的器官重量。心脏重量还与舒尔茨和乔达诺发表的数据（《病理学档案》。1962年；74:464 - 471）以及凯尔曼森的数据（《欧洲儿科学杂志》。1996年；155:440 - 444）进行了比较。这种比较显示出细微差异，本文对此进行了讨论。我们建议，SIDS病例中获得的器官重量可作为生命第一年的标准。
