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A centromere map of the X chromosome from trisomies of maternal origin.

作者信息

Morton N E, Keats B J, Jacobs P A, Hassold T, Pettay D, Harvey J, Andrews V

机构信息

CRC Research Group in Genetic Epidemiology, Department of Community Medicine, Southhampton General Hospital, UK.

出版信息

Ann Hum Genet. 1990 Jan;54(1):39-47. doi: 10.1111/j.1469-1809.1990.tb00359.x.

Abstract

A centromere map is derived from XXX and XXY trisomies of maternal origin. Preliminary data suggest reduced recombination in the tetrads giving rise to mei I nondisjunction, but an excess of recombination in the pericentric region. As in Drosophila, multichiasmate tetrads may be more at risk of nondisjunction than nullochiasmate tetrads.

摘要

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