Johansen K, Skotnicki A, Tan J C, Kwaasi A A, Skotnicki M
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Clin Genet. 1990 Mar;37(3):194-7. doi: 10.1111/j.1399-0004.1990.tb03502.x.
We studied the polymorphic locus in the A-I/C-III gene cluster on the long arm of chromosome 11 in 147 Saudi Arabian, in 84 Filipino and in 69 Caucasian blood donors. Digestion of DNA yielded two fragments 4.2 kb and 3.2 kb long. The genotype distribution was the same in Arabs and Filipinos, but both were significantly different from Caucasians (p = 0.005 and 0.0005). The 3.2-kb allele occurred in 18% of the Saudi Arabians, in 23% of the Filipinos and in 4% of Caucasians. The frequency of the 3.2-kb allele was significantly higher in Arabs and Filipinos compared to Caucasians (p = 0.0005).
我们研究了147名沙特阿拉伯献血者、84名菲律宾献血者和69名高加索献血者11号染色体长臂上A-I/C-III基因簇中的多态性位点。DNA消化产生了两条长度分别为4.2 kb和3.2 kb的片段。阿拉伯人和菲律宾人的基因型分布相同，但两者均与高加索人有显著差异（p = 0.005和0.0005）。3.2 kb等位基因出现在18%的沙特阿拉伯人、23%的菲律宾人和4%的高加索人中。与高加索人相比，阿拉伯人和菲律宾人中3.2 kb等位基因的频率显著更高（p = 0.0005）。
