Rashtak Shadi, Murray Joseph A
Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA.
Gastroenterol Clin North Am. 2009 Sep;38(3):433-46. doi: 10.1016/j.gtc.2009.06.005.
It has become apparent recently that celiac disease, once believed to be primarily a childhood disease, can affect people of any age. Epidemiologic studies have suggested that a substantial portion of patients are diagnosed after the age of 50. Indeed, in one study, the median age at the diagnosis was just under the age of 50 with one-third of new patients diagnosed being older than 65 years. The purpose of this review is to address the prevalence, clinical features, diagnosis, and consequences of celiac disease in the elderly. The authors also review management strategies for celiac disease and adjust these with emphasis on the particular nutritional and nonnutritional consequences or associations of celiac disease as they pertain to the elderly.
最近已经很明显,乳糜泻曾被认为主要是一种儿童疾病,现在可影响任何年龄段的人。流行病学研究表明,相当一部分患者是在50岁以后被诊断出来的。事实上,在一项研究中,诊断时的中位年龄刚好不到50岁,三分之一的新诊断患者年龄超过65岁。这篇综述的目的是探讨老年人乳糜泻的患病率、临床特征、诊断及后果。作者还综述了乳糜泻的管理策略,并根据与老年人相关的乳糜泻特殊营养和非营养后果或关联对这些策略进行调整。