Boucher A, Zine A, Jaziri F, Bernard N, Jeannoël P, Descotes J
Centre d'évaluation et d'information sur la pharmacodépendance (CEIP), hospices civils de Lyon, 162 avenue Lacassagne, Lyon cedex 03, France.
Arch Pediatr. 2009 Oct;16(10):1346-9. doi: 10.1016/j.arcped.2009.07.006. Epub 2009 Aug 21.
We describe an accidental ecstasy poisoning in a 10-month-old girl.
A 10-month-old infant suddenly exhibited behavior disorders with restlessness, hypertonia, and repetitive movements. She was immediately taken to the Emergency Department. Cardiovascular (tachycardia and hypertension) and neurological disorders (major agitation, mydriasis, and nystagmus) were the predominating clinical features. The most common differential diagnoses including febrile convulsion, cranial trauma, or encephalitis were progressively ruled out. The urinary toxicological screen was positive for methamphetamine. MDMA, its main metabolite, and caffeine were subsequently detected in the infant's urine using gas chromatography/mass spectrometry. The child had completely recovered the next morning.
Pediatric poisoning with ecstasy remains uncommon. To date, about 10 cases have been reported. All were due to accidental ingestion. Today, the use of ecstasy is no longer restricted to recreational purposes (rave parties, etc.) and it seems to be developing in private parties and in the home. The intrusion of this amphetamine-like drug into the domestic environment may expose young children to the accidental ingestion of ecstasy tablets.
我们描述了一名10个月大女童意外摇头丸中毒的病例。
一名10个月大的婴儿突然出现行为障碍，表现为烦躁不安、肌张力亢进和重复动作。她立即被送往急诊科。心血管系统紊乱（心动过速和高血压）和神经系统紊乱（严重躁动、瞳孔散大和眼球震颤）是主要临床特征。包括高热惊厥、颅脑外伤或脑炎在内的最常见鉴别诊断逐一被排除。尿液毒理学筛查显示甲基苯丙胺呈阳性。随后使用气相色谱/质谱法在婴儿尿液中检测到摇头丸、其主要代谢物和咖啡因。患儿第二天早上已完全康复。
儿童摇头丸中毒仍然不常见。迄今为止，已报告约10例病例。均因意外摄入所致。如今，摇头丸的使用不再局限于娱乐目的（狂欢派对等），似乎在私人派对和家庭中也有增多趋势。这种类似安非他命的药物进入家庭环境可能使幼儿面临意外摄入摇头丸片剂的风险。
