5-氨基水杨酸在轻或中度溃疡性直肠结肠炎短期治疗中的疗效和耐受性
[Efficacy and tolerability of 5-aminosalicylic acid in the short-term treatment of ulcerative rectocolitis during the mild or moderate stage].
作者信息
Bresci G, Carrai M, Venturini G, Gambardella L
机构信息
U.S.L. n. 12, Pisa, Divisione di Gastroenterologia.
出版信息
Minerva Dietol Gastroenterol. 1990 Jan-Mar;36(1):31-3.
PMID:1970855
Abstract
The aim of the study was to compare the efficacy and side-effects of 5-ASA and SASP in the treatment of active ulcerative colitis. An improvement was seen in 71.4% (5-ASA) and 70.3% (SASP) but there were no complete remissions. The incidence of improvements was only 36.3% (5-ASA) and 37.5% (SASP) in pancolitis. The side-effects appeared in 14.2% (5-ASA) and 21% (SASP).
摘要
该研究的目的是比较5-氨基水杨酸（5-ASA）和柳氮磺胺吡啶（SASP）治疗活动期溃疡性结肠炎的疗效和副作用。5-ASA组有71.4%的患者病情改善，SASP组为70.3%，但均无完全缓解。全结肠炎患者中，5-ASA组病情改善率仅为36.3%，SASP组为37.5%。5-ASA组副作用发生率为14.2%，SASP组为21%。
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