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食物过敏管理中的过敏原回避方法。

Allergen avoidance approaches in food allergy management.

作者信息

Koletzko Sibylle, Koletzko Berthold

机构信息

Division of Paediatric Gastroenterology and Hepatology, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.

出版信息

Nestle Nutr Workshop Ser Pediatr Program. 2009;64:169-80; discussion 180-4, 251-7. doi: 10.1159/000235790. Epub 2009 Aug 19.

Abstract

Dietary elimination of causative food ingredients, usually food proteins, is the basis of treating food hypersensitivity. Proper diagnostic assessment is essential to avoid burdening children with unnecessary dietary restrictions with potential adverse effects. Diagnosis requires a detailed history, allergen elimination, and re-challenge with suspected foods. Complete elimination of causative food components depends on professional counseling and training of the patient and family, and transparent labeling of food products. Elimination diets carry the risk of inducing insufficient supplies of critical nutrients with adverse effects on health and wellbeing, particularly in children with exclusion of foods that provide a major part of dietary supply and patients with multiple food allergies. Infants and young children with cow's milk allergy, who have not been fully breastfed, require milk substitutes based on extensively hydrolyzed protein or amino acids. Elimination diets must be supervised and monitored to a similar degree as drug treatments, and the need for continued dietary elimination should be reviewed on a regular basis and re-challenges considered.

摘要

通过饮食消除致病的食物成分,通常是食物蛋白,是治疗食物过敏的基础。进行恰当的诊断评估对于避免让儿童承受不必要的饮食限制及其潜在不良影响至关重要。诊断需要详细的病史、消除过敏原以及对可疑食物进行再激发试验。彻底消除致病的食物成分取决于对患者及其家人的专业咨询和培训,以及食品的清晰标签。排除饮食有导致关键营养素供应不足从而对健康和幸福产生不利影响的风险,尤其是对于那些排除了提供大部分饮食供应的食物的儿童以及患有多种食物过敏的患者。未进行充分母乳喂养的牛奶过敏婴幼儿需要以深度水解蛋白或氨基酸为基础的代乳品。排除饮食必须像药物治疗一样受到监督和监测,并且应定期复查是否需要继续进行饮食排除,并考虑进行再激发试验。

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