Saba Samir, Ravipati Lakshmi Prasad, Voigt Andrew
Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213-2582, USA.
Pacing Clin Electrophysiol. 2009 Nov;32(11):1444-9. doi: 10.1111/j.1540-8159.2009.02509.x. Epub 2009 Aug 27.
Cardiac arrest (CA) is a class I indication for implantable defibrillator (ICD) therapy. We studied the trend of ICD utilization in survivors of CA in the US population between 2002 and 2006.
We searched the National Hospital Discharge Survey for patients admitted with the primary diagnosis of CA who survived to hospital discharge. Patients with a concomitant diagnosis of acute myocardial infarction or previous ICD implantation were excluded.
From 2002 to 2006, 758 patients were surveyed representing 88,920 discharges. Of those, 396 (52.2%) representing 48,098 discharges did not survive to hospital discharge. Of the remaining 362 (representing 38,855) patients, 38.4% received an ICD prior to discharge. Independent predictors of in-hospital mortality included older age, female gender, black race, smaller hospital of discharge, and a higher number of organ failures (P<0.001 for all). Using logistic regression, patients who were discharged with an ICD were more likely to have been discharged from a larger hospital (odds ratio=2.35 for each additional 100 beds, P<0.001) and to be less sick (odds ratio=0.85 for each additional organ failure, P<0.001). There was no gender or racial discrepancy in the ICD utilization after CA.
Despite their class I indication after CA, ICDs continue to be underutilized, but the previously documented racial gaps have disappeared. Our data reveal a large discrepancy in ICD utilization by the size of the discharge hospital, which may suggest regional influences and gaps in resource allocations. Future studies looking into the root causes of these discrepancies and possible remedies are warranted.
心脏骤停(CA)是植入式除颤器(ICD)治疗的I类适应症。我们研究了2002年至2006年美国人群中CA幸存者ICD使用情况的趋势。
我们在国家医院出院调查中搜索了以CA为主要诊断入院且存活至出院的患者。排除伴有急性心肌梗死诊断或既往植入ICD的患者。
2002年至2006年,共调查了758例患者,代表88,920次出院。其中,396例(52.2%)代表48,098次出院的患者未存活至出院。其余362例(代表38,855次出院)患者中,38.4%在出院前接受了ICD植入。院内死亡的独立预测因素包括年龄较大、女性、黑人种族、出院医院规模较小以及器官衰竭数量较多(所有P<0.001)。使用逻辑回归分析,出院时植入ICD的患者更有可能从规模较大的医院出院(每增加100张床位,优势比=2.35,P<0.001)且病情较轻(每增加一个器官衰竭,优势比=0.85,P<0.001)。CA后ICD使用在性别或种族方面无差异。
尽管CA后有I类适应症,但ICD的使用仍未得到充分利用,但先前记录的种族差距已消失。我们的数据显示,出院医院规模不同,ICD使用存在很大差异,这可能表明存在区域影响和资源分配差距。有必要开展进一步研究,探究这些差异的根本原因及可能的补救措施。