Lai Chung-Yu, Tsai Shih-Hung, Lin Fu-Huang, Chu Hsin, Ku Chih-Hung, Wu Chun-Hsien, Chung Chi-Hsiang, Chien Wu-Chien, Tsai Ching-Tsan, Hsu Huan-Ming, Chu Chi-Ming
Graduate Institute of Medical Sciences, National Defense Medical Center Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center School of Public Health, National Defense Medical Center Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei City Department of Health Industry Management, Kainan University, Taoyuan City Division of Cardiology, Tri-Service General Hospital, National Defense Medical Center, Taipei City Big Data Research Center, Fu-Jen Catholic University, New Taipei City Department of Public Health, China Medical University, Taichung City Department of Surgery, Tri-Service General Hospital Songshan Branch, National Defense Medical Center, Taipei City Department of Healthcare Administration and Medical Informatics, College of Health Sciences, Kaohsiung Medical University Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung City, Taiwan.
Medicine (Baltimore). 2018 Jul;97(28):e11480. doi: 10.1097/MD.0000000000011480.
Studies regarding the prognostic factors for survival conditions and the proportions of survival to discharge among different types of hospitalized traumatic cardiac arrest (TCA) during the period of postresuscitation are limited.This nationwide study was designed to determine certain parameters and clarify the effect of various injuries on the survival of hospitalized TCA patients to discharge.Data were retrieved from the National Health Insurance Research Database (NHIRD) from 2007 to 2013 in Taiwan. We reviewed patients with a diagnosis of TCA using International Classification of Disease Clinical Modification, 9th revision codes (ICD-9-CM codes). Patients identified for analysis were simultaneously coded in traumatic etiology (ICD-9-CM codes: 800-999) and cardiac arrest (ICD-9-CM codes: 427.41 or 427.5). The determinants and effects of different types of injury on survival were evaluated by SPSS 22.0 (IBM, Armonk, NY).A total of 3481 cases of hospitalized TCA were selected from the NHIRD. The overall rate of survival to discharge was 22.1%. The results indicated a decreased adjusted odds ratio (aOR) of survival to discharge with higher numbers of organ failure (aOR: 0.82; 95% confidence interval [CI]: 0.73-0.92). Patients with ventricular fibrillation had a better discharge rate (aOR: 4.33; 95% CI: 3.29-5.70). Two parameters, transfer to another hospital and the number of intensive care unit beds, were positively correlated with survival. Compared with traffic accidents, different injuries associated with survival to discharge were identified; the aOR (95% CI) was 1.89 (1.12-3.19) for poisoning, 1.63 (1.13-2.36) for falls, and 2.00 (1.36-2.92) for drowning/suffocation.This study has shown that hospitalized TCA patients with multiple organ failure may be less likely to be discharged from the hospital. The presence of ventricular fibrillation rhythm on admission increased the odds of survival to discharge. In the phase of postcardiac arrest care, the number of intensive care unit beds and transfer to another hospital were positively correlated with survival. Those events attributed to traffic accidents have a much worse influence on the main outcome.
关于复苏后不同类型住院创伤性心脏骤停(TCA)患者生存状况的预后因素以及出院生存率的研究有限。这项全国性研究旨在确定某些参数,并阐明各种损伤对住院TCA患者出院生存的影响。数据取自台湾2007年至2013年的国民健康保险研究数据库(NHIRD)。我们使用国际疾病分类临床修订版第9版编码(ICD - 9 - CM编码)对诊断为TCA的患者进行了回顾。确定用于分析的患者同时具有创伤病因编码(ICD - 9 - CM编码:800 - 999)和心脏骤停编码(ICD - 9 - CM编码:427.41或427.5)。使用SPSS 22.0(IBM,纽约州阿蒙克)评估不同类型损伤对生存的决定因素和影响。
从NHIRD中选取了3481例住院TCA病例。总体出院生存率为22.1%。结果表明,器官衰竭数量越多,出院生存的调整后优势比(aOR)越低(aOR:0.82;95%置信区间[CI]:0.73 - 0.92)。室颤患者的出院率更高(aOR:4.33;95% CI:3.29 - 5.70)。两个参数,转院至另一家医院和重症监护病房床位数量,与生存呈正相关。与交通事故相比,确定了与出院生存相关的不同损伤;中毒的aOR(95% CI)为1.89(1.12 - 3.19),跌倒为1.63(1.13 - 2.36),溺水/窒息为2.00(1.36 - 2.92)。
本研究表明,多器官衰竭的住院TCA患者出院的可能性可能较小。入院时存在室颤节律增加了出院生存的几率。在心脏骤停后护理阶段,重症监护病房床位数量和转院至另一家医院与生存呈正相关。那些归因于交通事故的事件对主要结局的影响要大得多。