Jha Om P, Khurana Divya S, Carvalho Karen S, Melvin Joseph J, Legido Agustin, O'Riordan Anna C, Valencia Ignacio
Section of Neurology, St. Christopher's Hospital for Children, Department of Pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania 19134, USA.
J Child Neurol. 2010 Mar;25(3):284-6. doi: 10.1177/0883073809338521. Epub 2009 Aug 27.
The interpretation of QT interval is often neglected during electroencephalography (EEG) reading. We compared the incidence of prolonged QT interval, as seen in the electrocardiography (ECG) recording lead of the EEG, in children presenting with seizure, syncope, or attention-deficit hyperactivity disorder (ADHD). Abnormal QT was defined as >460 ms. The incidence of prolonged QT in the seizure, syncope, and ADHD groups was 1/50 (2%), 7/50 (14%), and 2/50 (4%), respectively (P = .036, chi-square). The mean +/- SD of QT were 405 +/- 34, 424 +/- 39, and 414 +/- 36, respectively (P = .035, analysis of variance [ANOVA], syncope group, compared with seizure group). The incidence of prolonged QT as measured in the EEG was unexpectedly high in children presenting with seizure, syncope, or ADHD. These data support the concept that QT evaluation should be emphasized during routine EEG reading, as it may aid in identifying cases of undiagnosed cardiac conduction abnormalities. Prospective studies comparing EEG-ECG tracings with 12-lead ECG are warranted.
在脑电图（EEG）解读过程中，QT间期的解读常常被忽视。我们比较了癫痫、晕厥或注意力缺陷多动障碍（ADHD）患儿脑电图记录导联心电图（ECG）中QT间期延长的发生率。QT异常定义为>460毫秒。癫痫组、晕厥组和ADHD组QT间期延长的发生率分别为1/50（2%）、7/50（14%）和2/50（4%）（P = 0.036，卡方检验）。QT间期的平均值±标准差分别为405±34、424±39和414±36（P = 0.035，方差分析[ANOVA]，晕厥组与癫痫组比较）。癫痫、晕厥或ADHD患儿脑电图测量的QT间期延长发生率意外地高。这些数据支持在常规脑电图解读过程中应强调QT评估的观点，因为这可能有助于识别未诊断的心脏传导异常病例。有必要进行前瞻性研究，将脑电图-心电图描记与12导联心电图进行比较。
