Bhattacharyya Neil, Lin Harrison W
Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.
Otolaryngol Head Neck Surg. 2009 Sep;141(3):311-5. doi: 10.1016/j.otohns.2009.06.010.
Determine reliability of self-reported authorship disclosures of potential conflicts of interest in American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF)-sponsored presentations and publications.
STUDY DESIGN/SETTING: Retrospective cohort study at academic center.
Presenters' self-reported disclosures made at the AAO-HNSF annual meeting for calendar years 2006 and 2007 were tabulated. Subsequent publications related to these presentations in the journal Otolaryngology-Head and Neck Surgery were analyzed with respect to disclosures revealed at the time of publication. Discrepancies between annual meeting disclosures and publication print disclosures were identified according to author and presentation/paper. Reliability statistics were computed to determine consistency of disclosure reporting and an analysis of potential conflicts of interest according to discrepancies was performed.
Five hundred seventy-eight presenters' disclosures were identified at the annual meeting level, which ultimately led to 153 journal publications. A total of 51 authors (8.8%) with disclosure reporting discrepancies were identified (32 authors: one discrepancy; 11 authors: two discrepancies; eight authors: three or more discrepancies). Overall, a mean of 0.14 discrepancies per author (95% confidence interval: 0.10-0.19 discrepancies) was noted. Analyzed by publication, 39 papers (25.5%) contained one or more disclosure discrepancies among authors, ranging from one discrepancy (11.8% of papers) to nine discrepancies (0.7%), with an average of 2.1 authorship disclosure discrepancies per paper.
A significant percentage of authors' disclosures differ between time of presentation and subsequent publication within otolaryngology. Although valid reasons for these discrepancies may exist, analysis of these discrepancies is important for conflict-of-interest determination.
确定在美国耳鼻咽喉 - 头颈外科学会基金会(AAO - HNSF)主办的演讲和出版物中,自我报告的潜在利益冲突作者披露的可靠性。
研究设计/地点:在学术中心进行的回顾性队列研究。
将2006年和2007年在AAO - HNSF年会上演讲者自我报告的披露情况制成表格。随后,对发表在《耳鼻咽喉 - 头颈外科》杂志上与这些演讲相关的出版物进行分析,以了解发表时披露的情况。根据作者以及演讲/论文,确定年会披露与出版物印刷版披露之间的差异。计算可靠性统计数据以确定披露报告的一致性,并根据差异对潜在利益冲突进行分析。
在年会层面确定了578名演讲者的披露情况,这些披露最终产生了153篇期刊出版物。共确定了51名作者(8.8%)存在披露报告差异(32名作者:一处差异;11名作者:两处差异;8名作者:三处或更多差异)。总体而言,每位作者平均有0.14处差异(95%置信区间:0.10 - 0.19处差异)。按出版物分析,39篇论文(25.5%)在作者之间存在一处或多处披露差异,差异范围从一处(占论文的11.8%)到九处(0.7%),每篇论文平均有2.1处作者披露差异。
在耳鼻咽喉科领域,很大一部分作者在演讲时和随后发表时的披露情况存在差异。尽管这些差异可能有合理原因,但对这些差异进行分析对于确定利益冲突很重要。