胸腺素诱导的人血清因子增加环磷酸腺苷。
Thymosin-induced human serum factor increasing cyclic AMP.
作者信息
Astaldi A, Astaldi G C, Wijermans P, Groenewoud M, Schellekens P T, Eijsvoogel V P
出版信息
J Immunol. 1977 Sep;119(3):1106-8.
Thymosin has virtually no in vitro effect on cyclic AMP levels in thymocytes and seems not to react with either the beta-adrenergic receptor or with the putative human serum thymic factor (SF) receptor. However, when thymosin is injected into patients lacking SF activity, it induces the appearance of a serum factor which increases cellular cyclic AMP levels in thymocytes in vitro. This factor appears to act on a membrane site distinct from the beta-adrenergic receptors.
胸腺素对胸腺细胞中的环磷酸腺苷（cAMP）水平几乎没有体外效应，而且似乎既不与β-肾上腺素能受体反应，也不与假定的人血清胸腺因子（SF）受体反应。然而，当将胸腺素注射到缺乏SF活性的患者体内时，它会诱导一种血清因子的出现，这种因子在体外可提高胸腺细胞中的细胞环磷酸腺苷水平。该因子似乎作用于一个与β-肾上腺素能受体不同的膜位点。
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