• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Hepatitis B virus in tenofovir-naive Chinese patients with chronic hepatitis B contains no mutation of rtA194T conferring a reduced tenofovir susceptibility.

作者信息

Liu Yan, Wang Chun-mei, Cheng Jun, Liang Zhao-ling, Zhong Yan-wei, Ren Xiao-qiang, Xu Zhi-hui, Zoulim Fabien, Xu Dong-ping

机构信息

Viral Hepatitis Research Laboratory, Institute of Infectious Diseases, Beijing 302 Hospital, Beijing 100039, China.

出版信息

Chin Med J (Engl). 2009 Jul 5;122(13):1585-6.

PMID:19719953
Abstract
摘要

相似文献

1
Hepatitis B virus in tenofovir-naive Chinese patients with chronic hepatitis B contains no mutation of rtA194T conferring a reduced tenofovir susceptibility.在初治的慢性乙型肝炎中国患者中，乙肝病毒不存在rtA194T突变，该突变会导致对替诺福韦的敏感性降低。
Chin Med J (Engl). 2009 Jul 5;122(13):1585-6.
2
Evidence of long-term suppression of hepatitis B virus DNA by tenofovir as rescue treatment in patients coinfected by HIV.替诺福韦作为挽救治疗对合并感染HIV患者的乙型肝炎病毒DNA长期抑制的证据。
Antivir Ther. 2008;13(3):341-8.
3
[Therapy of chronic hepatitis B. Tenofovir--first choice in current EASL guidelines].[慢性乙型肝炎的治疗。替诺福韦——当前欧洲肝脏研究学会（EASL）指南中的首选药物]
MMW Fortschr Med. 2009 May 28;151(22):38-9.
4
Molecular analysis of an HBsAg-negative hepatitis B virus mutant selected in a tenofovir-treated HIV-hepatitis B virus co-infected patient.在接受替诺福韦治疗的HIV-乙肝病毒合并感染患者中筛选出的HBsAg阴性乙肝病毒突变体的分子分析
AIDS. 2009 Jan 14;23(2):268-72. doi: 10.1097/QAD.0b013e3283224316.
5
Tenofovir for treatment of hepatitis B virus reactivation in patients with chronic GVHD.
Bone Marrow Transplant. 2011 Sep;46(9):1274-5. doi: 10.1038/bmt.2010.290. Epub 2010 Dec 13.
6
Tenofovir treatment in patients with lamivudine-resistant hepatitis B mutants strongly affects viral replication.替诺福韦治疗拉米夫定耐药乙型肝炎突变患者对病毒复制有强烈影响。
Hepatology. 2002 Aug;36(2):507-8. doi: 10.1053/jhep.2002.35328.
7
Tenofovir salvage for nucleoside experienced patients: muddy waters?
Gut. 2011 Feb;60(2):148-50. doi: 10.1136/gut.2010.229062.
8
Variability of reverse transcriptase and overlapping S gene in hepatitis B virus isolates from untreated and lamivudine-resistant chronic hepatitis B patients.未经治疗和对拉米夫定耐药的慢性乙型肝炎患者的乙肝病毒分离株中逆转录酶和重叠S基因的变异性
Antivir Ther. 2009;14(5):649-54.
9
Selection of K65R mutation in HIV-2-infected patients receiving tenofovir-containing regimen.
Antivir Ther. 2004 Aug;9(4):635-6.
10
Potency of tenofovir in chronic hepatitis B: mono or combination therapy?替诺福韦在慢性乙型肝炎中的效力：单药治疗还是联合治疗？
J Hepatol. 2008 Mar;48(3):383-6. doi: 10.1016/j.jhep.2007.12.006. Epub 2007 Dec 31.

引用本文的文献

1
Phylogenetic Analysis and Emerging Drug Resistance against Different Nucleoside Analogues in Hepatitis B Virus Positive Patients.乙肝病毒阳性患者中针对不同核苷类似物的系统发育分析及新出现的耐药性
Microorganisms. 2023 Oct 24;11(11):2622. doi: 10.3390/microorganisms11112622.
2
Host immunity and HBV S gene mutation in HBsAg-negative HBV-infected patients.HBV 感染患者中 HBsAg 阴性与宿主免疫及 HBV S 基因突变的关系。
Front Immunol. 2023 Aug 14;14:1211980. doi: 10.3389/fimmu.2023.1211980. eCollection 2023.
3
Molecular detection of hepatitis B virus genotype E with immune escape mutations in chronic hepatitis B patients on long-term antiviral therapy in Jos, Nigeria.
尼日利亚乔斯地区接受长期抗病毒治疗的慢性乙型肝炎患者中乙型肝炎病毒E基因型及免疫逃逸突变的分子检测
Afr J Lab Med. 2022 Oct 18;11(1):1677. doi: 10.4102/ajlm.v11i1.1677. eCollection 2022.
4
Hepatitis B virus DNA polymerase gene polymorphism based prediction of genotypes in chronic HBV patients from Western India.基于乙肝病毒DNA聚合酶基因多态性对印度西部慢性乙肝患者基因型的预测
Afr Health Sci. 2017 Sep;17(3):762-772. doi: 10.4314/ahs.v17i3.19.
5
Efficacy and Safety of Tenofovir Disoproxil Treatment for Chronic Hepatitis B Patients with Genotypic Resistance to Other Nucleoside Analogues: A Prospective Study.替诺福韦酯治疗对其他核苷类似物存在基因型耐药的慢性乙型肝炎患者的疗效与安全性：一项前瞻性研究。
Chin Med J (Engl). 2017 Apr 20;130(8):914-919. doi: 10.4103/0366-6999.204107.
6
Association between hepatitis B virus basal core promoter/precore region mutations and the risk of hepatitis B-related acute-on-chronic liver failure in the Chinese population: an updated meta-analysis.乙肝病毒核心启动子/前核心区突变与中国人群乙肝相关慢加急性肝衰竭风险的关联：一项更新的荟萃分析
Hepatol Int. 2016 Jul;10(4):606-15. doi: 10.1007/s12072-016-9716-7. Epub 2016 Mar 16.
7
Detection and analysis of resistance mutations of hepatitis B virus.乙型肝炎病毒耐药突变的检测与分析
Int J Clin Exp Med. 2015 Jun 15;8(6):9630-9. eCollection 2015.
8
Dynamic changes of HBV markers and HBV DNA load in infants born to HBsAg(+) mothers: can positivity of HBsAg or HBV DNA at birth be an indicator for HBV infection of infants?乙肝表面抗原（HBsAg）阳性母亲所生婴儿的乙肝病毒（HBV）标志物及HBV DNA载量的动态变化：出生时HBsAg或HBV DNA阳性能否作为婴儿HBV感染的指标？
BMC Infect Dis. 2013 Nov 6;13:524. doi: 10.1186/1471-2334-13-524.
9
Profile of hepatitis B virus resistance mutations against nucleoside/nucleotide analogue treatment in Chinese patients with chronic hepatitis B.中国慢性乙型肝炎患者核苷（酸）类似物治疗耐药相关乙型肝炎病毒基因突变特征。
Virol J. 2013 Oct 25;10:313. doi: 10.1186/1743-422X-10-313.
10
Hepatitis B virus (HBV) subgenotypes C2 and B2 differ in lamivudine- and adefovir-resistance-associated mutational patterns in HBV-infected Chinese patients.乙型肝炎病毒（HBV）亚基因型 C2 和 B2 在拉米夫定和阿德福韦耐药相关的突变模式方面存在差异，这与中国 HBV 感染患者有关。
J Clin Microbiol. 2010 Dec;48(12):4363-9. doi: 10.1128/JCM.01518-10. Epub 2010 Sep 29.