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[后部皮质萎缩]

[Posterior cortical atrophy].

作者信息

Maillet Didier, Moroni Christine, Belin Catherine

机构信息

UF mémoire et Maladie Neurodégénérative, Service de Neurologie, CHU Avicenne, AP-HP, Bobigny.

出版信息

Psychol Neuropsychiatr Vieil. 2009 Sep;7(3):193-203. doi: 10.1684/pnv.2009.0169.

Abstract

Posterior cortical atrophy belongs to the progressive focal atrophy group of neurodegenerative diseases. It is characterized by specific clinical deficits in visual perception, which can affect either visuo-spatial features or identity of objects. The posterior cortical atrophy, initially described by Pick in 1902, is a rare and not well known syndrome. While it is easy to differentiate posterior cortical atrophy from Alzheimer's disease, some cognitive deficits are common with those of Lewy body disease and corticobasal degeneration, which results in diagnostic mistakes. This paper proposes a synthetic review of the posterior cortical atrophy illustrated by a clinical case.

摘要

后部皮质萎缩属于神经退行性疾病的进行性局灶性萎缩组。其特征是在视觉感知方面存在特定的临床缺陷,这可能会影响视觉空间特征或物体的识别。后部皮质萎缩最初由皮克于1902年描述,是一种罕见且鲜为人知的综合征。虽然很容易将后部皮质萎缩与阿尔茨海默病区分开来,但一些认知缺陷与路易体病和皮质基底节变性的认知缺陷有共同之处,这就导致了诊断错误。本文通过一个临床病例对后部皮质萎缩进行综合综述。

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