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自体血源性干细胞移植后的感染。

Infection after autologous blood-derived stem cell transplantation.

作者信息

D'Antonio D, Iacone A, Fioritoni G, Angelini A, Dragani A, Betti S, Di Bartolomeo P, Di Bartolomeo G, Accorsi P, Quaglietta A M

机构信息

Divisione di Ematologia e Centro Trasfusionale, Ospedale Civile, Pescara, Italy.

出版信息

Haematologica. 1990 Jan-Feb;75 Suppl 1:83-6.

PMID:1972135
Abstract

Ten patients who underwent autologous blood-derived stem cell transplantation (APBSCT) were studied retrospectively to determine the frequency and outcome of transplant associated infections during the hemopoietic reconstitution. Six patients developed an infection after transplant. Severe bacterial infections were unfrequent and mostly caused by gram-positive cocci. In no case pneumonia was observed and this scarce morbility of infection could be the result of early engraftment. None of them died for infection. The frequency of infections in APBSCT patients appears lower than the one observed in autologous bone marrow transplant patients.

摘要

对10例行自体血源性干细胞移植(APBSCT)的患者进行回顾性研究,以确定造血重建期间移植相关感染的发生率及转归。6例患者移植后发生感染。严重细菌感染不常见,主要由革兰氏阳性球菌引起。未观察到肺炎病例,这种感染发病率低可能是早期植入的结果。无一例因感染死亡。APBSCT患者的感染发生率似乎低于自体骨髓移植患者。

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