Martinez Del Pero Marcos, Lloyd Simon K W, Moffat David A
Department of Neurotology and Skullbase Surgery, Cambridge University Hospitals NHS Trust, Addenbrooke's Hospital, Cambridge, United Kingdom.
Skull Base. 2009 Mar;19(2):159-62. doi: 10.1055/s-0028-1096203.
Vestibular schwannomas are benign, slow-growing tumors that originate from Schwann cells lining the vestibular nerves, most commonly the superior vestibular nerve. They arise at the neurilemmal/neuroglial junction which is situated within the internal auditory canal. They have an incidence of 1 per 100,000 per year and a prevalence of around 700 per million. A case of a patient undergoing a period of observation for a vestibular schwannoma whose hearing improved despite growth of the tumor is described. This raises interesting questions regarding the pathophysiology of hearing loss in patients with vestibular schwannomas. Possible hypotheses are discussed.
前庭神经鞘瘤是一种良性、生长缓慢的肿瘤,起源于前庭神经周围的施万细胞,最常见于上前庭神经。它们发生在内耳道内的神经膜/神经胶质交界处。其年发病率为十万分之一,患病率约为百万分之700。本文描述了一例前庭神经鞘瘤患者在观察期内,尽管肿瘤生长但听力却有所改善的病例。这就引发了关于前庭神经鞘瘤患者听力损失病理生理学的有趣问题。文中讨论了可能的假设。