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结核分枝杆菌液体培养:可行,但需谨慎。

Liquid culture for Mycobacterium tuberculosis: proceed, but with caution.

作者信息

Anthony R M, Cobelens F G J, Gebhard A, Klatser P R, Lumb R, Rüsch-Gerdes S, van Soolingen D

机构信息

Royal Tropical Institute, KIT Biomedical Research, Amsterdam, The Netherlands.

出版信息

Int J Tuberc Lung Dis. 2009 Sep;13(9):1051-3.

PMID:19723391
Abstract

Attempts to improve the diagnosis of tuberculosis (TB) in high-burden countries has resulted in significant funding and initiatives to change the method of diagnosis of TB from light microscopy supplemented with X-ray to a sophisticated diagnostic algorithm based on the latest technological innovations. Such activities are overdue and should be welcomed, but the lack of skills and support available to interpret and use the results represents a danger. The introduction of new diagnostic methods, particularly liquid culture, should be carefully structured according to the local situation, failing which frustration and the disruption of previously underdeveloped but adequately functioning laboratories may result.

摘要

在高负担国家,为改善结核病(TB)诊断所做的努力已带来大量资金和举措,旨在将结核病诊断方法从辅以X射线的光学显微镜检查转变为基于最新技术创新的精密诊断算法。此类活动早就该开展了,理应受到欢迎,但缺乏解读和利用诊断结果所需的技能及支持却构成了一种风险。新诊断方法的引入,尤其是液体培养法的引入,应根据当地情况精心安排,否则可能导致挫败感,并使之前虽不发达但运转良好的实验室陷入混乱。

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