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香港的大咯血:病因、血管造影结果及支气管动脉栓塞术的疗效

Major haemoptysis in Hong Kong: aetiologies, angiographic findings and outcomes of bronchial artery embolisation.

作者信息

Chan V L, So L K Y, Lam J Y M, Lau K-Y, Chan C-S, Lin A W N, Chu C-M

机构信息

Department of Medicine & Geriatrics, United Christian Hospital, Hong Kong, SAR China.

出版信息

Int J Tuberc Lung Dis. 2009 Sep;13(9):1167-73.

PMID:19723409
Abstract

SETTING

Tertiary referral centres.

OBJECTIVE

To provide comprehensive updates on the aetiologies, angiographic findings and outcomes of bronchial artery embolisation (BAE) for life-threatening haemoptysis in Hong Kong.

DESIGN

Retrospective review of clinical records of consecutive patients presenting with life-threatening haemoptysis from 2000 to 2006.

RESULTS

There were 3006 admissions due to haemoptysis involving 2260 patients during the study period; of these, 251 patients had life-threatening haemoptysis. Pulmonary tuberculosis (PTB) (active or inactive) and bronchiectasis were the main underlying causes. BAE was attempted in 167 patients. There was a high prevalence of bilateral bronchial arterial abnormalities (31.7%), presence of abnormal non-bronchial arteries (41.3%) and presence of broncho-pulmonary shunt (38.9%). BAE had a high immediate success rate of 95.7%, with a 5-year recurrence rate of 45.0%. Recurrent life-threatening haemoptysis was independently associated with past history of haemoptysis (P = 0.024), presence of broncho-pulmonary shunt (P = 0.013), and incomplete embolisation (P = 0.002). Complications were uncommon (<5%) and self-limiting.

CONCLUSIONS

In Hong Kong, about one tenth of admissions due to haemoptysis were life-threatening. PTB and bronchiectasis were the major causes. Complications due to BAE were uncommon and self-limiting, with super-selective catheters.

摘要

背景

三级转诊中心。

目的

全面更新香港地区危及生命咯血的支气管动脉栓塞术(BAE)的病因、血管造影结果及治疗效果。

设计

对2000年至2006年期间连续出现危及生命咯血的患者临床记录进行回顾性分析。

结果

研究期间,因咯血入院3006例,涉及2260名患者;其中251例患者出现危及生命的咯血。肺结核(活动期或非活动期)和支气管扩张是主要潜在病因。167例患者尝试进行BAE。双侧支气管动脉异常(31.7%)、存在异常非支气管动脉(41.3%)和存在支气管肺分流(38.9%)的发生率较高。BAE的即刻成功率高达95.7%,5年复发率为45.0%。复发性危及生命咯血与咯血既往史(P = 0.024)、支气管肺分流的存在(P = 0.013)和栓塞不完全(P = 0.002)独立相关。并发症少见(<5%)且为自限性。

结论

在香港,约十分之一的咯血入院患者存在生命危险。肺结核和支气管扩张是主要病因。使用超选择性导管时,BAE引起的并发症少见且为自限性。

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