Szeifert Lilla, Hamvas Szilárd, Adorjáni Gertrúd, Novák Márta
Semmelweis Egyetem, Altalános Orvostudományi Kar Magatartástudományi Intézet Budapest.
Orv Hetil. 2009 Sep 13;150(37):1723-30. doi: 10.1556/OH.2009.28698.
Depression is a common co-morbid condition in patients suffering from a variety of chronic medical conditions. In spite of this, mental health of patients with chronic kidney disease is understudied. Accurate estimation of the prevalence of depressive disorders in this population is difficult due to the different definitions and assessment techniques and the overlap of depressive symptomatology with symptoms of uremia. Several potential pathways link depression and chronic kidney disease. The association between the two conditions is probably bidirectional. Consequently, treatment of mood disorders could impact medical outcome. Very little has been published about the therapeutic options for depression in patients with chronic kidney disease. Available data, however, suggest that several antidepressant medications and psychotherapeutic methods are likely to be safe and effective also in this population. In this review, which is the second of a series of reviews on this topic, we provide an overview of the literature concerning the diagnosis, screening and therapy of depressive disorders in patients with chronic kidney disease.
抑郁症是患有各种慢性疾病的患者中常见的共病情况。尽管如此，慢性肾脏病患者的心理健康仍未得到充分研究。由于定义和评估技术不同以及抑郁症状与尿毒症症状重叠，准确估计该人群中抑郁症的患病率很困难。抑郁症和慢性肾脏病之间存在多种潜在联系。这两种情况之间的关联可能是双向的。因此，情绪障碍的治疗可能会影响医疗结果。关于慢性肾脏病患者抑郁症治疗选择的文献报道很少。然而，现有数据表明，几种抗抑郁药物和心理治疗方法在该人群中可能也是安全有效的。在本综述中，这是关于该主题的一系列综述中的第二篇，我们概述了有关慢性肾脏病患者抑郁症诊断、筛查和治疗的文献。
